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A class of Escherichia coli proteins controlled by the hflA locus.

作者信息

Cheng H H, Echols H

机构信息

Department of Molecular Biology, University of California, Berkeley 94720.

出版信息

J Mol Biol. 1987 Aug 5;196(3):737-40. doi: 10.1016/0022-2836(87)90046-5.

DOI:10.1016/0022-2836(87)90046-5
PMID:2824788
Abstract

The HflA protein of Escherichia coli is critical for the choice of the lytic or lysogenic pathway by bacteriophage lambda. To investigate whether HflA plays a regulatory role in E. coli, we used two-dimensional gel electrophoresis to compare the distribution of E. coli proteins in hflA+ and hflA- cells. We found at least 13 proteins that are present in hflA- strains, but absent or very low in hflA+ strains. This observation indicates that HflA might be involved in regulation of a large class of E. coli proteins. Because of prior work implicating the Crp/cAMP system in Hfl-mediated regulation of lambda, we also studied the distribution of E. coli proteins in cya- strains unable to synthesize cAMP. Some of the same proteins found in hflA- are elicited by the addition of cAMP to cya- cells.

摘要

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引用本文的文献

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BMC Microbiol. 2011 Feb 17;11:34. doi: 10.1186/1471-2180-11-34.
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Potential role of proteolysis in the control of UvrABC incision.蛋白水解作用在UvrABC切口控制中的潜在作用。
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Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells.
噬菌体λ感染的大肠杆菌细胞中发育途径分叉的随机动力学分析。
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