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索马里索马里兰博拉马结核病控制项目评估

Evaluation of Borama tuberculosis control program in Somaliland, Somalia.

作者信息

Qayad Mohamed Gedi, Tarsitani Gianfranco

机构信息

University of Rome-Sapienza, Rome, Italy.

出版信息

J Infect Dev Ctries. 2017 Feb 28;11(2):115-122. doi: 10.3855/jidc.7676.

Abstract

INTRODUCTION

The Borama TB program in Somalia lost resources for TB operations in 2003. We evaluated the impact of the loss on the program.

METHODOLOGY

Pre-event (2002-2003) and post-event (2007) design were used. All TB patients registered in Borama and a sample of four months from Hargeisa (comparison) TB patients in both periods were abstracted. The following TB treatment outcomes were estimated: treatment success, treatment failure, case fatality, treatment interruption and transfer rates, along with percentage of patients with sputum specimen prior to treatment, percentage of patients from neighboring countries, and monthly average patients enrolled in treatment. The pre-event to post-event outcomes and measures were compared using descriptive and multivariate analyses.

RESULTS

In total, 3,367 TB cases were abstracted. In Borama, the TB treatment success rate increased 6% in the post-event. The treatment failure and interruption rates both declined 75%. Monthly average TB patients declined 55%. Percentage of patients smear tested prior to the initiation of the treatment declined 9%. Percentage of TB patients from neighboring countries and other parts of Somalia declined 51%. Treatment interruption/transfer rates declined significantly in the post-event, compared to the pre-event period. Treatment failure/death rate did not change in the post-event period. In Hargeisa, the treatment success, failure/death, and interruption/transfer rates were similar in both periods. The RR did not change in these measures after adjusting for age and gender.

CONCLUSIONS

This study indicates a significant setback to the Borama TB control program in the majority of measures evaluated, except the TB success rate.

摘要

引言

索马里博拉马结核病项目在2003年失去了结核病防治资源。我们评估了资源损失对该项目的影响。

方法

采用事件前(2002 - 2003年)和事件后(2007年)设计。提取了博拉马登记的所有结核病患者以及同期哈尔格萨(对照)结核病患者四个月的样本。估计了以下结核病治疗结果:治疗成功率、治疗失败率、病死率、治疗中断和转出率,以及治疗前有痰标本的患者百分比、来自邻国的患者百分比和每月平均接受治疗的患者数。使用描述性和多变量分析比较了事件前后的结果和指标。

结果

总共提取了3367例结核病病例。在博拉马,事件后的结核病治疗成功率提高了6%。治疗失败率和中断率均下降了75%。每月平均结核病患者数下降了55%。治疗开始前接受涂片检查的患者百分比下降了9%。来自邻国和索马里其他地区的结核病患者百分比下降了51%。与事件前相比,事件后的治疗中断/转出率显著下降。事件后治疗失败/死亡率没有变化。在哈尔格萨,两个时期的治疗成功率、失败/死亡率和中断/转出率相似。在调整年龄和性别后,这些指标的相对风险没有变化。

结论

本研究表明,除了结核病成功率外,在大多数评估指标上,博拉马结核病控制项目遭受了重大挫折。

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