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中间普雷沃菌感染导致急性复杂性主动脉炎——病例报告

Prevotella intermedia infection causing acute and complicated aortitis-A case report.

作者信息

Boersma C, Kampschreur L M, Buter H, Doorenbos B M, Klinkert P, Koning G G

机构信息

Medical Center Leeuwarden, Henri Dunantweg 2, 8934 AD Leeuwarden, The Netherlands (5).

Medical Center Leeuwarden, Henri Dunantweg 2, 8934 AD Leeuwarden, The Netherlands (5).

出版信息

Int J Surg Case Rep. 2017;32:58-61. doi: 10.1016/j.ijscr.2017.02.015. Epub 2017 Feb 20.

Abstract

INTRODUCTION

Aortitis is a general term that refers to all conditions involving an inflammation of the aortic wall. This case report describes the surgical approach of a patient with infectious and symptomatic aortitis caused by the rare vector Prevotella intermedia.

PRESENTATION OF CASE

A 44-year old male patient was admitted with fever and general discomfort after a period of sore throat in a non-teaching hospital. After two weeks he developed acute abdominal and back pain accompanied by sweating and elevated infection parameters. Computed tomography angiography revealed atherosclerotic changes of the infrarenal aorta with a locally contained rupture of the aorta alongside peri-aortal signs of inflammation (and aortitis aspects). An urgent aortic reconstruction was performed according to Nevelsteen. The blood cultures turned out positive for Prevotella intermedia. Postoperatively the patient received antibiotics for six weeks. The patient recovered uneventful from this infection and surgical procedure.

DISCUSSION

A complicated and acute aortitis is a rare but potentially life-threatening disease. The aetiology can be ordered into two main groups; inflammatory and infectious. Diagnosis is based upon symptoms, biochemical values, microbiological results and imaging modalities. Treatment depends on aetiology and should be discussed in an experienced multidisciplinary setting. Infectious aortitis should be treated with antibiotics for at least six weeks with close monitoring of the patient's clinic and biochemical values, even after surgery.

CONCLUSION

Prevotella intermedia is a rare causative agent for aortitis. Acute aortitis is a challenging clinical entity which should be managed in an equipped medical center by an experienced multidisciplinary team.

摘要

引言

主动脉炎是一个通用术语,指涉及主动脉壁炎症的所有病症。本病例报告描述了一名由罕见病原体中间普雷沃菌引起的感染性和症状性主动脉炎患者的手术方法。

病例介绍

一名44岁男性患者在一家非教学医院经历一段时间的喉咙痛后,因发热和全身不适入院。两周后,他出现急性腹痛和背痛,伴有出汗和感染指标升高。计算机断层扫描血管造影显示肾下腹主动脉有动脉粥样硬化改变,主动脉局部破裂,伴有主动脉周围炎症体征(以及主动脉炎表现)。根据内夫尔斯泰因方法进行了紧急主动脉重建。血培养结果显示中间普雷沃菌呈阳性。术后患者接受了六周的抗生素治疗。患者从此次感染和手术中顺利康复。

讨论

复杂的急性主动脉炎是一种罕见但可能危及生命的疾病。病因可分为两大类;炎症性和感染性。诊断基于症状、生化指标、微生物学结果和影像学检查。治疗取决于病因,应在经验丰富的多学科环境中进行讨论。即使在手术后,感染性主动脉炎也应用抗生素治疗至少六周,并密切监测患者的临床症状和生化指标。

结论

中间普雷沃菌是主动脉炎的罕见致病因素。急性主动脉炎是一个具有挑战性的临床实体,应由经验丰富的多学科团队在设备齐全的医疗中心进行管理。

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