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一名患有超广谱β-内酰胺酶阳性相关的气肿性远端腹主动脉炎并迅速发展为囊状动脉瘤的患者成功接受了血管内治疗。

A successful endovascular treatment of a patient with extended-spectrum beta-lactamase positive related emphysematous distal abdominal aortitis rapidly progressing to a saccular aneursym.

作者信息

Mirzamidinov Didar, Karauzum Kurtulus, Kahraman Nail, Cakir Ozgur, Karauzum Irem, Ural Ertan, Sahin Tayfun

机构信息

Kocaeli University Medicine School Cardiology Department, Kocaeli, Turkey.

Bursa City Hospital Cardiovascular Surgery Depatment, Bursa, Turkey.

出版信息

J Cardiol Cases. 2023 Feb 14;27(5):215-217. doi: 10.1016/j.jccase.2023.02.002. eCollection 2023 May.

Abstract

UNLABELLED

Infectious aortitis is a rare disease and associated with adverse clinical outcomes. A 66-year-old man was admitted to the emergency department with abdominal and lower back pain, fever, chills, and anorexia continuing for a week. A contrast-enhanced computed tomography (CT) scan of the abdomen showed multiple periaortic enlarged lymphatic nodes, mural wall thickening, and gas collections in the infrarenal aorta and proximal segment of right common iliac artery. The patient was hospitalized with the diagnosis of acute emphysematous aortitis. During hospitalization, extended-spectrum beta-lactamase-positive was grown in all blood and urine cultures. Despite sensitive antibiotherapy, abdominal and back pain, inflammation biomarkers, and fever of the patient were not improved. Control CT demonstrated a newly developed mycotic aneurysm, increased intramural gas collection, and periaortic soft-tissue thickening. Urgent vascular surgery was recommended to the patient by the heart team, but the patient rejected surgery due to the high perioperative risk. Alternatively, an endovascular rifampin-impregnated stent-graft was successfully implanted and antibiotics were completed at 8 weeks. After procedure, inflammatory indicators were normalized and clinical symptoms of the patient were resolved. No microorganism grew on control blood and urine cultures. The patient was discharged with a good health.

LEARNING OBJECTIVE

Aortitis should be suspected in patients who present with fever, abdominal and back pain, especially in the presence of predisposing risk factors. Infectious aortitis (IA) accounts for a small part of all aortitis cases and the most common causative microorganism is . The mainstay treatment of IA is sensitive antibiotherapy. Surgery may be required in patients who are unresponsive to antibiotics or develop aneurysm. Alternatively, endovascular treatment can be performed in selected cases.

摘要

未标注

感染性主动脉炎是一种罕见疾病,与不良临床结局相关。一名66岁男性因腹部和下背部疼痛、发热、寒战及厌食持续一周而入住急诊科。腹部增强计算机断层扫描(CT)显示腹主动脉周围多个肿大淋巴结、血管壁增厚,以及肾下腹主动脉和右髂总动脉近端段有气体积聚。该患者因急性气肿性主动脉炎诊断入院。住院期间,所有血培养和尿培养均培养出产超广谱β-内酰胺酶菌。尽管采用了敏感抗菌治疗,但患者的腹部和背部疼痛、炎症生物标志物及发热均未改善。对照CT显示新出现的真菌性动脉瘤、壁内气体积聚增加及腹主动脉周围软组织增厚。心脏团队建议患者紧急行血管手术,但患者因围手术期风险高而拒绝手术。作为替代方案,成功植入了血管内利福平浸渍支架移植物,并在8周时完成了抗生素治疗。术后,炎症指标恢复正常,患者临床症状消失。对照血培养和尿培养未培养出微生物。患者健康出院。

学习目标

对于出现发热、腹部和背部疼痛的患者,尤其是存在易感危险因素时,应怀疑主动脉炎。感染性主动脉炎(IA)占所有主动脉炎病例的一小部分,最常见的致病微生物是 。IA的主要治疗方法是敏感抗菌治疗。对抗生素无反应或发生动脉瘤的患者可能需要手术。作为替代方案,可在特定病例中进行血管内治疗。

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本文引用的文献

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Emphysematous aortitis: report of two cases and CT imaging findings.气肿性主动脉炎:两例报告及CT影像表现
BJR Case Rep. 2017 Apr 6;3(3):20170006. doi: 10.1259/bjrcr.20170006. eCollection 2017.
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Infectious Aortitis.感染性主动脉炎
Curr Treat Options Cardiovasc Med. 2005 Jun;7(2):89-97. doi: 10.1007/s11936-005-0010-6.

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