Panteliadis Christos P, Vassilyadi Photios, Fehlert Julia, Hagel Christian
Division of Pediatric Neurology and Developmental Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Department of Internal Medicine, St. John Hospital & Medical Center, Detroit, MI, USA.
Brain Dev. 2017 Jun;39(6):457-463. doi: 10.1016/j.braindev.2017.02.002. Epub 2017 Feb 27.
Historical documents dating back almost 4500years have alluded to the condition of epilepsy, describing signs and symptoms that are well-known today. Epilepsy was thought to be a mystical disorder by almost all Ancient cultures, including the Babylonians, Egyptians, Greeks, Indians, Iranians and Chinese. Hippocrates was the first to de-mystify the condition of epilepsy, providing a more scientific approach to the condition. As the signs and symptoms of epilepsy occurred without an obvious cause, the idea stood that it was a mystical phenomenon of divine punishment. This portrayal persisted through the early centuries of the common era, including the Middle Ages. It was not until the 16th and 17th century that Paracelsus, le Pois and Sylvius started to investigate internal causes for epilepsy. By the beginning of the 18th century, the general opinion on epilepsy was that it was an idiopathic disease residing in the brain and other inner organs. This resulted in Tissot writing the first modern book on epilepsy. Research continued in the 19th century with Jackson describing different types of seizures and many researchers showing interest in electroencephalography (EEG). The 20th century saw more detailed research being done on epilepsy and EEG, in addition to the establishment of many epilepsy-associated medical societies. The goal of this historical documentation is to provide an overview of the most important milestones in the history of epilepsy.
可追溯到近4500年前的历史文献已经提及了癫痫病症，描述了如今广为人知的体征和症状。几乎所有古代文化，包括巴比伦人、埃及人、希腊人、印度人、伊朗人和中国人，都认为癫痫是一种神秘的疾病。希波克拉底是第一个破除癫痫神秘性的人，他为这种病症提供了一种更科学的研究方法。由于癫痫的体征和症状在没有明显病因的情况下出现，所以人们认为这是一种神罚的神秘现象。这种描述一直持续到公元后的最初几个世纪，包括中世纪。直到16世纪和17世纪，帕拉塞尔苏斯、勒普瓦和西尔维于斯才开始研究癫痫的内在病因。到18世纪初，关于癫痫的普遍看法是，它是一种存在于大脑和其他内脏器官的特发性疾病。这促使蒂索写出了第一本关于癫痫的现代书籍。19世纪研究仍在继续，杰克逊描述了不同类型的癫痫发作，许多研究人员对脑电图（EEG）产生了兴趣。20世纪，除了成立了许多与癫痫相关的医学协会外，人们对癫痫和脑电图进行了更详细的研究。这份历史文献的目的是概述癫痫历史上最重要的里程碑。
