[环孢素治疗下的双侧睫状体水肿]

[Bilateral ciliary body oedema under treatment with ciclosporine].

作者信息

Braun R, Holler E, Wolff D, Helbig H, Blecha C, Dietrich-Ntoukas T

机构信息

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

Klinik und Poliklinik für Innere Medizin III, Universitätsklinikum Regensburg, Regensburg, Deutschland.

出版信息

Ophthalmologe. 2018 Jan;115(1):55-58. doi: 10.1007/s00347-017-0475-1.

DOI:10.1007/s00347-017-0475-1

PMID:28251308

Abstract

We present the case of a 27-year-old female patient who developed bilateral ciliary body edema with secondary glaucoma and myopic shift during systemic treatment with cyclosporine for aplastic anemia. After application of topical atropine and prednisolone acetate and conversion from cyclosporine to tacrolimus, the ophthalmologic symptoms resolved completely. Since an infectious etiology was not evident, we hypothesize that ciliary body edema was caused by impairment of microvascular integrity by cyclosporine.

摘要

我们报告了一例27岁女性患者，该患者在接受环孢素系统性治疗再生障碍性贫血期间出现双侧睫状体水肿，并继发青光眼和近视移位。在应用局部阿托品和醋酸泼尼松龙，并将环孢素转换为他克莫司后，眼科症状完全缓解。由于感染病因不明显，我们推测睫状体水肿是由环孢素对微血管完整性的损害引起的。