Tellkamp H, Köhler K, Barke R
Klinik für Radiologie der Medizinischen Akademie, Carl Gustav Carus, Dresden.
Rofo. 1987 Oct;147(4):379-85. doi: 10.1055/s-2008-1048661.
722 CT examinations were carried out in 178 patients having intracranial tumours. The CT changes resulting from radiotherapy have been analysed. The examinations were performed at the beginning of treatment, after 30 and 50 Gy, after a three months' pause and at the conclusion of the planned total irradiation with 70 Gy. The results indicate that CT of intracranial tumours is an excellent method of demonstrating the effect of treatment. Information regarding the surroundings of the tumour (eg. cerebral oedema, displacement, herniation, compression of the ventricular system etc.) may be as important as that concerning the tumour itself. For evaluating the effect of radiation therapy, measurements of the size of the tumour are much more informative than density measurements. Even after 30 Gy, there was a change in tumour size in 49% of patients. Planned CT control used in conjunction with clinical information provides an effective means of adapting treatment to the changes in the tumour.
对178例颅内肿瘤患者进行了722次CT检查。分析了放疗引起的CT变化。检查在治疗开始时、30 Gy和50 Gy后、三个月的间歇期以及计划的70 Gy全照射结束时进行。结果表明，颅内肿瘤的CT检查是显示治疗效果的极佳方法。有关肿瘤周围情况（如脑水肿、移位、疝形成、脑室系统受压等）的信息可能与肿瘤本身的信息同样重要。为评估放射治疗效果，测量肿瘤大小比测量密度更具信息价值。即使在30 Gy照射后，49%的患者肿瘤大小也有变化。计划的CT对照结合临床信息提供了一种根据肿瘤变化调整治疗的有效方法。
