Glaser F H, Basche S, Gaerisch F, Haberland N, Keiner P, Keinert K, Pothe H, Steube D
Klinik und Poliklinik für Radiologie, Medizinische Akademie Erfurt.
Rev Med Chir Soc Med Nat Iasi. 1991 Jul-Dec;95(3-4):275-8.
Interstitial brachytherapy of intracerebral tumours was stimulated through the introduction of computed tomography and afterloading technique. Biopsies for their histologic verification as well as the stereotactic implantation of plastic tubes and adjusted to the extent of the tumour can be carried out with a high degree of exactitude by means of CT-supported localization and puncture. The small-sized 198-gold seeds are then introduced according to the manual afterloading technique and remain in situ until the planned dose in the target volume of 50 Gy is achieved. Report on our manual afterloading brachytherapy in high-grade astrocytomas III and IV and in adenomas of the hypophysis. Indications of the diagnostic and therapeutic procedure, irradiation planning, calculation of the dose and discussion of our tentative clinical experience are explained.
计算机断层扫描和后装技术的引入推动了脑肿瘤间质近距离放射治疗的发展。借助计算机断层扫描辅助定位和穿刺，能够高度精确地进行活检以进行组织学验证，以及立体定向植入塑料管并使其与肿瘤范围相适配。然后根据手动后装技术引入小尺寸的198金籽源，并使其留在原位，直至靶体积达到计划的50戈瑞剂量。报告我们在III级和IV级高级别星形细胞瘤以及垂体腺瘤中进行的手动后装近距离放射治疗。解释了诊断和治疗程序的适应症、放射治疗计划、剂量计算以及我们初步临床经验的讨论。
