Oncol Res Treat. 2017;40(3):120-127. doi: 10.1159/000458443. Epub 2017 Feb 24.
The number of patients with HIV (human immunodeficiency virus) requiring treatment for malignancy is increasing worldwide. Concurrent treatment of HIV and malignancy is complicated by unpredictable drug-drug interactions, which can cause potentially life-threatening toxicities and ineffective treatment of either disease. This article aims to provide a practical approach to drug interactions and their management in this context to help deliver effective and safe treatment of both the malignancy and HIV.
全球需要治疗恶性肿瘤的 HIV(人类免疫缺陷病毒)患者数量正在增加。同时治疗 HIV 和恶性肿瘤会受到不可预测的药物相互作用的影响,这可能导致危及生命的毒性和两种疾病的治疗无效。本文旨在提供一种实用的方法来处理这种情况下的药物相互作用及其管理,以帮助提供有效和安全的恶性肿瘤和 HIV 治疗。