Oncol Res Treat. 2017;40(3):100-105. doi: 10.1159/000456715. Epub 2017 Feb 24.
Anal carcinoma shows an increasing incidence in people living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) in whom it is also much more common compared to the HIV-negative population. Human papillomavirus infection is the etiological basis of malignant development in the anal epithelium. Therefore, adequate diagnosis and treatment of the precursor lesions (anal intraepithelial neoplasia) is of clinical importance. In cases with preserved immune function, anal cancer can be treated according to guidelines issued for HIV-negative patients. This review summarizes the current knowledge regarding anal malignancies in HIV-positive patients.
肛门癌在人类免疫缺陷病毒 (HIV) 感染者和获得性免疫缺陷综合征 (AIDS) 患者中的发病率呈上升趋势，与 HIV 阴性人群相比，肛门癌在这些患者中更为常见。人乳头瘤病毒感染是肛门上皮恶性发展的病因基础。因此，充分诊断和治疗前体病变（肛门上皮内瘤变）具有重要的临床意义。在免疫功能正常的情况下，可以根据针对 HIV 阴性患者发布的指南对肛门癌进行治疗。本文综述了 HIV 阳性患者肛门恶性肿瘤的相关知识。
