Department of Psychiatry, University of Cambridge, Cambridge, Herchel Smith Building, CB2 0SZ Cambridge, UK.
Department of Psychiatry and Psychotherapy, Clinical Division of Social Psychiatry, Medical University Vienna, 1090 Vienna, Austria.
Schizophr Res. 2017 Nov;189:69-74. doi: 10.1016/j.schres.2017.02.017. Epub 2017 Feb 27.
A need for a brief, easy to complete self-report questionnaire to detect people at ultra-high risk for psychosis (UHR) in busy clinical settings has been recognised. Our aim was to explore whether the Community Assessment of Psychic Experiences - Positive 15-items Scale (CAPE-P15) could be used as a screening tool to identify people at UHR in a clinical setting. Our objectives were to confirm the CAPE-P15 factorial structure as well as its reliability and determine cut-off values for the detection of such individuals using the Comprehensive Assessment of At-Risk Mental States (CAARMS), a commonly used clinical interview for the detection of UHR. 165 participants aged between 13 and 18 referred to the General Hospital of Vienna were included in the analysis. 50.9% of the sample were "CAARMS-positive" and 49.1% "CAARMS-negative". The Youden method determined CAPE-P15 cut-off values for UHR detection of 1.47 for both frequency of and distress associated with psychotic experiences. The cut-off value of 1.47 for frequency showed sensitivity of 77%, specificity of 58%, a positive predictive value of 66% and a negative predictive value of 71%; whilst for distress it showed sensitivity of 73%, specificity of 63%, a positive predictive value of 69% and a negative predictive value of 66%. Good reliability and the previously suggested three-correlated factor model as well as an alternative bi-factor model of the CAPE-P15 were confirmed. The CAPE-P15 seems to be a promising screening tool for identifying people who might be at UHR in busy clinical settings.
在繁忙的临床环境中,需要一种简短、易于完成的自我报告问卷来检测处于精神病超高风险(UHR)的人群,这一点已经得到了认可。我们的目的是探讨社区心理体验评估-阳性 15 项量表(CAPE-P15)是否可以用作筛选工具,以在临床环境中识别处于 UHR 的人群。我们的目标是确认 CAPE-P15 的因子结构及其可靠性,并确定使用广泛用于检测 UHR 的综合风险精神状态评估(CAARMS)检测此类个体的截止值。共纳入了 165 名年龄在 13 至 18 岁之间的维也纳综合医院就诊的参与者。该样本中有 50.9%的人“CAARMS 阳性”,49.1%的人“CAARMS 阴性”。Youden 法确定了 CAPE-P15 用于检测 UHR 的截止值,即与精神病体验的频率和相关痛苦分别为 1.47。频率的截止值为 1.47,其敏感性为 77%,特异性为 58%,阳性预测值为 66%,阴性预测值为 71%;而对于痛苦,其敏感性为 73%,特异性为 63%,阳性预测值为 69%,阴性预测值为 66%。CAPE-P15 具有良好的可靠性,证实了之前提出的三相关因子模型以及 CAPE-P15 的替代双因子模型。CAPE-P15 似乎是一种有前途的筛选工具,可以识别出可能处于繁忙临床环境中 UHR 的人群。