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不同剂量利多卡因用于牛精索阻滞的麻醉效果

Anesthetic effects of different volumes of lidocaine for spermatic cord block in cattle.

作者信息

Neves Ana C, Santos Júnior Juracy Cb, Marucio Rodrigo L, Midon Monica, Luna Stelio Pl

机构信息

Faculty of Veterinary Medicine Universidade Estácio de Sá (UNESA), Vargem Pequena, RJ, Brazil.

Department of Veterinary Medicine and Surgery, Institute of Veterinary Medicine, Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropedica, RJ, Brazil.

出版信息

Vet Anaesth Analg. 2017 Mar;44(2):375-378. doi: 10.1016/j.vaa.2016.05.002. Epub 2017 Jan 7.

DOI:10.1016/j.vaa.2016.05.002
PMID:28254529
Abstract

OBJECTIVE

To evaluate three volumes of lidocaine for spermatic cord block to perform castration in cattle.

STUDY DESIGN

Randomized blinded clinical study.

ANIMALS

Thirty mixed-breed Nellore cattle, aged 28-40 months and weighing 395±21 (352-452) kg [mean±standard deviation (range)].

METHODS

Cattle were restrained in a chute and allowed to stand without sedation. Three milliliters of 2% lidocaine without epinephrine were infiltrated subcutaneously at each site of scrotal incision in all animals. The animals were allocated to three groups of 10 animals each. Lidocaine 2% was injected into each spermatic cord using a volume of 2, 3 or 4 mL in groups A, B, or C, respectively. The total volumes of lidocaine used were 10, 12, and 14 mL in groups A, B, and C, respectively. The duration of surgery and the retraction of the testicle (scored as positive or negative according to retraction of the testicle) during the procedure were recorded. The data were statistically analyzed by one-way anova followed by Tukey's and chi-square tests. Differences were considered significant when p<0.05.

RESULTS

The mean surgical time was shorter in group C than in groups A and B (p<0.001). In groups A, B and C, 90%, 60% and 10% of the animals showed retraction of the testicle, respectively. Fewer animals retracted the spermatic cord in group C than in group A (p=0.002) and B (p=0.02).

CONCLUSIONS AND CLINICAL RELEVANCE

Optimal spermatic cord block was achieved by injection of 4 mL of 2% lidocaine 5 minutes before castration and following incisional infiltration of lidocaine, in adult cattle weighing about 400 kg.

摘要

目的

评估三种剂量的利多卡因用于牛精索阻滞以实施去势手术的效果。

研究设计

随机双盲临床研究。

动物

30头杂种内洛尔牛,年龄28 - 40个月,体重395±21(352 - 452)千克[平均值±标准差(范围)]。

方法

将牛限制在斜槽中,不使用镇静剂使其站立。所有动物在阴囊切口的每个部位皮下注射3毫升不含肾上腺素的2%利多卡因。将动物分为三组,每组10头。分别在A组(2毫升)、B组(3毫升)或C组(4毫升)的每条精索中注射2%利多卡因。A组、B组和C组使用的利多卡因总量分别为10毫升、12毫升和14毫升。记录手术持续时间以及手术过程中睾丸的回缩情况(根据睾丸回缩情况分为阳性或阴性)。数据采用单因素方差分析,随后进行Tukey检验和卡方检验进行统计学分析。当p<0.05时,差异被认为具有统计学意义。

结果

C组的平均手术时间比A组和B组短(p<0.001)。在A组、B组和C组中,分别有90%、60%和10%的动物出现睾丸回缩。C组精索回缩的动物比A组(p = 0.002)和B组(p = 0.02)少。

结论及临床意义

对于体重约400千克的成年牛,在去势前5分钟注射4毫升2%利多卡因并在切口浸润利多卡因后,可实现最佳的精索阻滞效果。

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