Jenkins D J, Peterson R D, Thorne M J, Ferguson P W
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto.
Am J Gastroenterol. 1987 Dec;82(12):1259-63.
We studied the dose response to soft white winter wheat fiber on fecal output in a group of healthy volunteers whose breakfasts consisted of wheat fiber cereals in amounts that provided 0.3 g, 5.6 g, 9.5 g, 11.2 g, 19.0 g, and 28.4 g dietary fiber per day for 14 days; no other aspects of their diet were altered. A linear dose response was observed between the six levels of fiber intake (r = 0.983, p less than 0.01) with a 1-g increase in wheat fiber, producing a mean 2.7-g increase in fecal weight. This increase was independent of the initial daily fecal weight of the volunteer (mean 117 +/- 64 g/day, range 5-297 g/day, n = 73). The maximum increase in fecal output due to cereal fiber was reached after the first week on the supplement. These data support the use of graded amounts of cereal fiber in the management of constipation.
我们对一组健康志愿者进行了研究，观察软质白冬小麦纤维对粪便排出量的剂量反应。这些志愿者连续14天早餐食用含小麦纤维的谷类食品，每天膳食纤维摄入量分别为0.3克、5.6克、9.5克、11.2克、19.0克和28.4克；他们饮食的其他方面未作改变。在六个纤维摄入量水平之间观察到线性剂量反应（r = 0.983，p小于0.01），小麦纤维每增加1克，粪便重量平均增加2.7克。这种增加与志愿者最初的每日粪便重量无关（平均117±64克/天，范围5 - 297克/天，n = 73）。补充膳食纤维的第一周后，谷类纤维导致的粪便排出量增加达到最大值。这些数据支持在便秘管理中使用不同剂量的谷类纤维。
