Nick S, Metzger B, Jonsić S, Falke D
Division of Experimental Virology, Johannes Gutenberg-University, Mainz, Federal Republic of Germany.
Arch Virol. 1987;97(1-2):131-5. doi: 10.1007/BF01310741.
HSV-2 infections suppress the antibody response to HSV-1 but do not impair the mouse cytomegalo virus (MCMV) antibody generating system. In contrast, the sheep red blood cell (SRBC) IgM response is impaired by preinfections with HSV-2 but not with HSV-1. From the time kinetics of this suppression it can be concluded that only a certain submechanism "spills over" to the SRBC system. MCMV suppresses the antibody formation induced by HSV-1.
单纯疱疹病毒2型(HSV - 2)感染会抑制机体对单纯疱疹病毒1型(HSV - 1)的抗体反应,但不会损害小鼠巨细胞病毒(MCMV)抗体产生系统。相比之下,HSV - 2预感染会损害绵羊红细胞(SRBC)IgM反应,而HSV - 1预感染则不会。从这种抑制作用的时间动力学可以得出结论,只有特定的子机制“溢出”到SRBC系统。MCMV会抑制HSV - 1诱导的抗体形成。