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印度阿萨姆邦焦尔哈特镇伤寒热暴发的流行病学调查。

Epidemiological investigation of an outbreak of typhoid fever in Jorhat town of Assam, India.

作者信息

Roy Jashbeer Singh, Saikia Lahari, Medhi Mithu, Tassa Dipak

机构信息

Department of Microbiology, Assam Medical College & Hospital, Dibrugarh, India.

出版信息

Indian J Med Res. 2016 Oct;144(4):592-596. doi: 10.4103/0971-5916.200902.

DOI:10.4103/0971-5916.200902
PMID:28256469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5345307/
Abstract

BACKGROUND & OBJECTIVES: Typhoid fever is a global health problem and is also endemic in India. An outbreak of fever occurred in January 2014 in Jorhat Town in Assam, India. Here we report the results of an investigation done to find out the aetiology and source of the outbreak.

METHODS

The affected areas were visited on January 23, 2014 by a team of Jorhat district Integrated Disease Surveillance Project personnel. A total of 13 blood samples from patients with fever as first symptom and six water samples were collected from the affected areas. The blood samples were cultured and isolates were identified using standard biochemical tests. Isolates were also tested for antimicrobial sensitivity. Widal test was performed on 10 of the 13 blood samples collected. Sanitary survey was carried out to find any leakage in the water supply and also the sewage system of the Jorhat town.

RESULTS

Blood culture yielded Salmonella enterica serovar Typhi in six (46.15%) patients whereas Widal test was positive in 10 (76.9%) of 13 patients. Water culture showed presumptive coliform count of >180/100 ml in two out of the six samples tested. Salmonella Typhi was also isolated from water culture of these two samples. Sanitary survey carried out in the affected places showed that the water supply pipes of urban water supply were in close proximity to the sewage drainage system and there were few leakages.

INTERPRETATION & CONCLUSIONS: The outbreak occurred due to S. Typhi contaminating the water supply. Sanitation and immunization are the two most important components to be stressed to prevent such outbreaks.

摘要

背景与目的

伤寒热是一个全球性的健康问题,在印度也呈地方性流行。2014年1月,印度阿萨姆邦乔哈特镇爆发了一场热病疫情。在此,我们报告为查明此次疫情的病因和源头所开展的调查结果。

方法

2014年1月23日,乔哈特地区综合疾病监测项目的一组工作人员走访了受影响地区。共采集了13份以发热为首发症状患者的血样以及6份来自受影响地区的水样。对血样进行培养,并通过标准生化试验鉴定分离菌。还对分离菌进行了抗菌药敏试验。对所采集的13份血样中的10份进行了肥达试验。开展了卫生调查,以查找乔哈特镇供水系统及污水系统是否存在渗漏情况。

结果

血培养显示,6名(46.15%)患者感染了伤寒沙门氏菌,而13名患者中有10名(76.9%)的肥达试验呈阳性。水培养显示,在检测的6份水样中有2份的推定大肠菌群计数>180/100 ml。这两份水样的水培养中也分离出了伤寒沙门氏菌。在受影响地点开展的卫生调查显示,城市供水的水管靠近污水排水系统,且存在少量渗漏。

解读与结论

此次疫情是由伤寒沙门氏菌污染供水所致。卫生设施和免疫接种是预防此类疫情需要重点强调的两个最重要组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9f/5345307/595a6e99ad01/IJMR-144-592-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9f/5345307/595a6e99ad01/IJMR-144-592-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9f/5345307/595a6e99ad01/IJMR-144-592-g002.jpg

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