水通道蛋白的转运特性

Transport Characteristics of Aquaporins.

作者信息

Geng Xiaoqiang, Yang Baoxue

机构信息

Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, China.

出版信息

Adv Exp Med Biol. 2017;969:51-62. doi: 10.1007/978-94-024-1057-0_3.

DOI:10.1007/978-94-024-1057-0_3

PMID:28258565

Abstract

Aquaporins (AQPs ) are a class of the integral membrane proteins, which are permeable to water , some small neutral solutes and certain gases across biological membranes. AQPs are considered as critical transport mediators that are involved in many physiological functions and pathological processes such as transepithelial fluid transport , cell migration, brain edema , neuro excitation and carcinoma. This chapter will provide information about the transport characteristics of AQPs .

摘要

水通道蛋白（AQPs）是一类整合膜蛋白，可使水、一些小分子中性溶质和某些气体透过生物膜。水通道蛋白被认为是关键的转运介质，参与许多生理功能和病理过程，如跨上皮液体转运、细胞迁移、脑水肿、神经兴奋和癌症。本章将提供有关水通道蛋白转运特性的信息。