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波兰卢布林地区的人乳头瘤病毒疫苗接种情况

HPV Vaccinations in Lublin Region, Poland.

作者信息

Kalinowski Paweł, Grządziel Anna

机构信息

Independent Epidemiology Unit, Medical University of Lublin.

出版信息

Postepy Hig Med Dosw (Online). 2017 Feb 14;71(0):92-97. doi: 10.5604/01.3001.0010.3793.

Abstract

INTRODUCTION

Secondary prophylaxis of cervical cancer consisting in cytology screening tests, despite its effectiveness, does not achieve the desired results. For several years, primary prophylaxis has been available in the form of protective vaccinations. At present, two vaccine preparations are available on the market, and studies conducted on these preparations confirm their almost 100% effectiveness in the prevention of types of HPV present in the vaccine.

OBJECTIVE

Analysis of the programmes of protective vaccinations against HPV carried out during the period 2008-2013 in the Lublin Region.

MATERIAL/METHODS: The material used in the study was data obtained from the relevant organs of the territorial self-government concerning programmes of vaccinations against HPV, demographic data pertaining to girls aged 10-18 living in the Lublin Region, as well as data published by the National Institute of Public Health - National Institute of Hygiene (NIZP-PZH). The method applied in the study was analysis of records.

RESULTS

During the period 2008-2013, in the Lublin Region a total of 5,496 girls were vaccinated within the health programmes. The mean immunization coverage in Lublin is 50%, and in Radzyń Podlaski 59%. The percentage contribution of vaccinations guaranteed free by the local authorities, with relation to the total number of vaccinations performed in the Lublin Region, was from 60 to 77%. The units of territorial self-government allocated the amount of PLN 5,125,359 for the performance of projects associated with execution of free vaccinations.

DISCUSSION

Among the total number of girls vaccinated against HPV, a considerable percentage were those vaccinated within the prophylactic programmes carried out by the units of territorial self-government. The programmes of free protective vaccinations against HPV began in 4 cities in the Lublin Region, and are continued only in two (Lublin and Radzyń Podlaski). Long-term observation of girls subjected to vaccinations from the aspect of maintenance of the immune response after vaccination should become an important element of performance of health programmes concerning vaccinations against HPV.

CONCLUSIONS

Among the total number of girls vaccinated against HPV, those vaccinated within prophylactic programmes carried out by territorial self-government units made up a considerable percentage. Programmes of free preventive vaccinations against HPV began in 4 cities in the Lublin Region, but are continued in only 2. Long-term observation of girls subjected to vaccinations from the aspect of duration of maintaining immunity after vaccination should become an important element of the performance of health programmes concerning vaccinations against HPV.

摘要

引言

宫颈癌的二级预防包括细胞学筛查检测,尽管其有效,但并未达到预期效果。数年来,一级预防可通过保护性疫苗接种实现。目前,市场上有两种疫苗制剂,针对这些制剂开展的研究证实其在预防疫苗中所含人乳头瘤病毒(HPV)类型方面几乎具有100%的有效性。

目的

分析2008 - 2013年期间在卢布林地区开展的针对HPV的保护性疫苗接种计划。

材料/方法:研究中使用的材料是从地方自治相关机构获取的有关HPV疫苗接种计划的数据、卢布林地区10 - 18岁女孩的人口统计学数据,以及国家公共卫生研究所 - 国家卫生研究所(NIZP - PZH)公布的数据。研究采用的方法是记录分析。

结果

2008 - 2013年期间,卢布林地区共有5496名女孩在健康计划内接种了疫苗。卢布林的平均免疫覆盖率为50%,在拉济恩波德拉斯基为59%。地方当局免费提供的疫苗接种在卢布林地区总接种量中的占比为60%至77%。地方自治单位为执行与免费疫苗接种相关的项目拨款5,125,359兹罗提。

讨论

在接种HPV疫苗的女孩总数中,相当大比例是在地方自治单位开展的预防计划内接种的。针对HPV的免费保护性疫苗接种计划始于卢布林地区的4个城市,目前仅在两个城市(卢布林和拉济恩波德拉斯基)继续实施。从接种后免疫反应维持情况方面对接种疫苗的女孩进行长期观察应成为HPV疫苗接种健康计划实施的重要内容。

结论

在接种HPV疫苗的女孩总数中,在地方自治单位开展的预防计划内接种的占相当大比例。针对HPV的免费预防性疫苗接种计划始于卢布林地区的4个城市,但仅在2个城市继续实施。从接种后免疫持续时间方面对接种疫苗的女孩进行长期观察应成为HPV疫苗接种健康计划实施的重要内容。

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