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编辑评论：是时候为有症状的膝关节骨关节炎患者尝试关节内注射富血小板血浆了。

Editorial Commentary: The Time Has Come to Try Intra-articular Platelet-Rich Plasma Injections for Your Patients With Symptomatic Knee Osteoarthritis.

作者信息

Hunt Timothy J

出版信息

Arthroscopy. 2017 Mar;33(3):671-672. doi: 10.1016/j.arthro.2016.12.006.

DOI:10.1016/j.arthro.2016.12.006
PMID:28259349
Abstract

Platelet-rich plasma injections, in a systematic review and meta-analysis of 10 Level I randomized control trials, were found to provide more pain relief and better functional outcomes than hyaluronic acid in patients with knee osteoarthritis at 12 months after injection. The time has come for those of us who have not yet tried platelet-rich plasma injections in our patients with symptomatic knee osteoarthritis to do so.

摘要

在一项对10项I级随机对照试验的系统评价和荟萃分析中发现，对于膝骨关节炎患者，在注射后12个月时，富血小板血浆注射比透明质酸能提供更多的疼痛缓解和更好的功能结果。对于我们这些尚未在有症状的膝骨关节炎患者中尝试富血小板血浆注射的人来说，是时候这样做了。

相似文献

1
Editorial Commentary: The Time Has Come to Try Intra-articular Platelet-Rich Plasma Injections for Your Patients With Symptomatic Knee Osteoarthritis.编辑评论：是时候为有症状的膝关节骨关节炎患者尝试关节内注射富血小板血浆了。
Arthroscopy. 2017 Mar;33(3):671-672. doi: 10.1016/j.arthro.2016.12.006.
2
Intra-articular injection of Platelet rich plasma versus Hyaluronic acid for moderate knee osteoarthritis. A prospective, double-blind randomized controlled trial on 189 patients with follow-up for three years.关节内注射富血小板血浆与透明质酸治疗中度膝骨关节炎。一项前瞻性、双盲、随机对照试验，共纳入 189 例患者，随访 3 年。
Acta Orthop Belg. 2021 Dec;87(4):729-734. doi: 10.52628/87.4.18.
3
Does Intra-articular Platelet-Rich Plasma Injection Provide Clinically Superior Outcomes Compared With Other Therapies in the Treatment of Knee Osteoarthritis? A Systematic Review of Overlapping Meta-analyses.与其他疗法相比，关节腔内注射富血小板血浆在治疗膝关节骨关节炎方面是否能提供更优的临床疗效？对重叠荟萃分析的系统评价。
Arthroscopy. 2015 Nov;31(11):2213-21. doi: 10.1016/j.arthro.2015.03.041. Epub 2015 May 29.
4
Is local platelet-rich plasma injection clinically superior to hyaluronic acid for treatment of knee osteoarthritis? A systematic review of randomized controlled trials.局部富血小板血浆注射治疗膝骨关节炎优于透明质酸吗？一项随机对照试验的系统评价。
Arthritis Res Ther. 2018 Jun 19;20(1):128. doi: 10.1186/s13075-018-1621-0.
5
Intra-Articular Injections of Platelet-Rich Plasma versus Hyaluronic Acid in the Treatment of Osteoarthritic Knee Pain: A Randomized Clinical Trial in the Context of the Spanish National Health Care System.富血小板血浆与透明质酸关节腔内注射治疗膝骨关节炎疼痛的随机临床试验：西班牙国家医疗保健系统背景下的研究
Int J Mol Sci. 2016 Jul 2;17(7):1064. doi: 10.3390/ijms17071064.
6
Comparing the efficacy of different intra-articular injections for knee osteoarthritis: A network analysis.比较不同关节内注射治疗膝骨关节炎的疗效：网络分析。
Medicine (Baltimore). 2022 Aug 5;101(31):e29655. doi: 10.1097/MD.0000000000029655.
7
Editorial Commentary: Meta-analysis Shows That Platelet-Rich Plasma Is Safe and Effective for Knee Osteoarthritis: Future Randomized Controlled Trials Must Be of High Quality-Not High Quantity.社论评论：荟萃分析表明富血小板血浆对膝骨关节炎安全且有效：未来的随机对照试验必须高质量而非大量。
Arthroscopy. 2021 Jan;37(1):326-327. doi: 10.1016/j.arthro.2020.10.004.
8
Efficacy and safety profile of a compound composed of platelet-rich plasma and hyaluronic acid in the treatment for knee osteoarthritis (preliminary results).富含血小板血浆与透明质酸复合物治疗膝骨关节炎的疗效和安全性概况（初步结果）
Eur J Orthop Surg Traumatol. 2015 Dec;25(8):1321-6. doi: 10.1007/s00590-015-1693-3. Epub 2015 Sep 24.
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Editorial Commentary: Injections for Knee Osteoarthritis: Doc, You Gotta Help Me!社论评论：膝关节骨关节炎的注射治疗：医生，你一定要帮帮我！
Arthroscopy. 2021 Apr;37(4):1288-1289. doi: 10.1016/j.arthro.2020.12.228.
10
Editorial Commentary: Platelet-Rich Plasma or Profit-Rich Placebo: Variability of Composition, Concentration, Preparation, and Many Other Yet-Unknown Factors Determine Effectiveness.社论评论：富含血小板的血浆还是利润丰厚的安慰剂：组成、浓度、制备和许多其他未知因素的可变性决定了有效性。
Arthroscopy. 2019 Oct;35(10):2885-2886. doi: 10.1016/j.arthro.2019.06.015.

引用本文的文献

1
Single Injection of High Volume of Autologous Pure PRP Provides a Significant Improvement in Knee Osteoarthritis: A Prospective Routine Care Study.单次大剂量自体纯富血小板血浆注射治疗膝骨关节炎的疗效：一项前瞻性常规护理研究。
Int J Mol Sci. 2019 Mar 15;20(6):1327. doi: 10.3390/ijms20061327.