Ayvazoglu Soy Ebru H, Kirnap Mahir, Yildirim Sedat, Moray Gokhan, Haberal Mehmet
Department of General Surgery, Baskent University, Ankara, Turkey.
Exp Clin Transplant. 2017 Feb;15(Suppl 1):185-189. doi: 10.6002/ect.mesot2016.P65.
An incisional hernia seriously burdens the quality of life after liver transplant. The incidence of incisional hernia after liver transplant is reported to be 4% to 20%. Here, we evaluated incisional hernias that occurred after adult liver transplant and incisional hernias intentionally made in infant liver transplant procedures.
Between December 1988 and May 2016, we performed 536 liver transplant procedures in 515 patients. Demographic features, surgical outcomes, and predisposing factors were evaluated.
Of 452 liver transplant patients included, incisional hernias were diagnosed in 29 patients (6.4%; 7 pediatric, 22 adult). Most were males (77%) with Child-Pugh score C cirrhosis (62%), moderate/severe ascites (81%), and serum albumin levels <3.5 g/L (86%). Incisional hernia developed in 16 of 51 patients (31%) with wound infection. Twelve incisional hernias were seen in 40 recipients (30%) with body mass index ≥30 kg/m2. Eight of 45 patients (18%) with repeated surgery had incisional hernias. Five of 22 adult incisional hernias (23%) had primary fascia repair, and 17 (77%) were repaired with Prolene mesh graft (3 sublay, 14 onlay). No other complications and no hernia recurrence were shown during follow-up (range, 8-138 mo). Of 7 pediatric liver transplant patients with intentionally made incisional hernias during liver transplant, 5 patients had primary fascia repair and 2 patients had onlay mesh repair. No complications or recurrence were shown during follow-up (range, 12-60 mo).
Repeated surgery, postoperative wound infection, and obesity were found to be predisposing risk factors for incisional hernia development after liver transplant in adults. Abdomen closure in infant liver transplant with large-for-size grafts is a different area of discussion. Here, we suggest that an intentionally made incisional hernia with staged closure of the abdomen is safe and effective for graft and patient survival.
切口疝严重影响肝移植后的生活质量。据报道,肝移植后切口疝的发生率为4%至20%。在此,我们评估了成人肝移植后发生的切口疝以及婴儿肝移植手术中故意制造的切口疝。
1988年12月至2016年5月期间,我们对515例患者进行了536例肝移植手术。评估了人口统计学特征、手术结果和易感因素。
在纳入的452例肝移植患者中,29例(6.4%;7例儿童,22例成人)被诊断为切口疝。大多数为男性(77%),患有Child-Pugh C级肝硬化(62%)、中/重度腹水(81%)且血清白蛋白水平<3.5 g/L(86%)。51例伤口感染患者中有16例(31%)发生了切口疝。40例体重指数≥30 kg/m²的受者中有12例(30%)出现切口疝。45例接受重复手术的患者中有8例(18%)发生切口疝。22例成人切口疝中有5例(23%)进行了一期筋膜修复,17例(77%)采用普理灵网片修补(3例为腹膜前修补,14例为腹膜外修补)。随访期间(8至138个月)未出现其他并发症及疝复发。7例在肝移植期间故意制造切口疝的儿童肝移植患者中,5例进行了一期筋膜修复,2例进行了腹膜外网片修补。随访期间(12至60个月)未出现并发症或复发。
重复手术、术后伤口感染和肥胖是成人肝移植后切口疝发生的易感危险因素。对于使用超大尺寸移植物的婴儿肝移植,腹部关闭是一个不同的讨论领域。在此,我们建议故意制造切口疝并分期关闭腹部对移植物和患者的存活是安全有效的。