Department of Urology, SMS Medical College and Hospital, Jaipur, India.
Department of Urology, R G Kar Medical College and Hospital, Kolkata, India.
Investig Clin Urol. 2017 Mar;58(2):103-108. doi: 10.4111/icu.2017.58.2.103. Epub 2017 Feb 15.
Extracorporeal shock wave lithotripsy (ESWL) is an established modality for renal calculi. Its role for large stones is being questioned. A novel model of temporary double J (DJ) stenting followed by ESWL was devised and outcomes were assessed.
The study included 95 patients with renal calculi sized 1 to 2 cm. Patients were randomized into 3 groups. Group 1 received ESWL only, whereas group 2 underwent stenting followed by ESWL. In group 3, a distinct model was applied in which the stent was kept for 1 week and then removed, followed by ESWL. Procedural details, analgesic requirements, and outcome were analyzed.
Eighty-eight patients (male, 47; female, 41) were available for analysis. The patients' mean age was 37.9±10.9 years. Stone profile was similar among groups. Group 3 received fewer shocks (mean, 3,155) than did group 1 (mean, 3,859; p=0.05) or group 2 (mean, 3,872; p=0.04). The fragmentation rate was similar in group 3 (96.7%) and groups 1 (81.5%, p=0.12) and 2 (87.1%, p=0.16). Overall clearance in group 3 was significantly improved (83.3%) compared with that in groups 1 (63.0%, p=0.02) and 2 (64.5%, p=0.02) and was maintained even in lower pole stones. The percentage successful outcome in groups 1, 2, and 3 was 66.7%, 64.5%, and 83.3%, respectively (p=0.21). The analgesic requirement in group 2 was higher than in the other groups (p=0.00). Group 2 patients also had more grade IIIa (2/3) and IIIB (1/2) complications.
Stenting adversely affects stone clearance and also makes the later course uncomfortable. Our model of brief stenting followed by ESWL provided better clearance, comfort, and a modest improvement in outcome with fewer sittings and steinstrasse in selected patients with large renal calculi.
体外冲击波碎石术(ESWL)是治疗肾结石的一种成熟方法。但其治疗大结石的作用正受到质疑。我们设计了一种新的临时双 J(DJ)支架置入后行 ESWL 的模型,并评估了其结果。
本研究纳入了 95 例肾结石大小为 1 至 2cm 的患者。患者随机分为 3 组。第 1 组仅接受 ESWL,第 2 组接受支架置入后行 ESWL,第 3 组采用一种独特的模型,支架置入 1 周后取出,然后再行 ESWL。分析了操作细节、镇痛需求和结果。
88 例患者(男 47 例,女 41 例)纳入分析。患者平均年龄为 37.9±10.9 岁。3 组的结石特征相似。第 3 组接受的冲击波次数(平均 3155 次)少于第 1 组(平均 3859 次,p=0.05)或第 2 组(平均 3872 次,p=0.04)。第 3 组的碎石率(96.7%)与第 1 组(81.5%,p=0.12)和第 2 组(87.1%,p=0.16)相似。第 3 组的总体清除率(83.3%)明显高于第 1 组(63.0%,p=0.02)和第 2 组(64.5%,p=0.02),即使在下极结石中也能维持。第 1、2 和 3 组的成功结局百分比分别为 66.7%、64.5%和 83.3%(p=0.21)。第 2 组的镇痛需求高于其他组(p=0.00)。第 2 组患者还出现了更多的 IIIa(2/3)和 IIIB(1/2)级并发症。
支架置入会对结石清除产生不利影响,并且会使后期过程更加不适。我们的模型是短暂支架置入后行 ESWL,对于选择的大肾结石患者,可提供更好的清除效果、舒适度,并可减少碎石次数和 Steinstrasse,同时提高结局。