肉毒杆菌素联合肌筋膜松解物理疗法治疗肌筋膜性骨盆疼痛。

Botox combined with myofascial release physical therapy as a treatment for myofascial pelvic pain.

机构信息

Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL, USA.

Department of Female Pelvic Floor Medicine and Reconstructive Surgery, University of South Florida, Tampa, FL, USA.

出版信息

Investig Clin Urol. 2017 Mar;58(2):134-139. doi: 10.4111/icu.2017.58.2.134. Epub 2017 Feb 1.

Abstract

PURPOSE

To report the effects of combined onabotulinumtoxinA (Botox) injections and myofascial release physical therapy on myofascial pelvic pain (MFPP) by comparing pre- and posttreatment average pelvic pain scores, trigger points, and patient self-reported pelvic pain. Secondary outcomes were to examine posttreatment complications and determine demographic differences between patients with/without an improvement in pain.

MATERIALS AND METHODS

This was an Institutional Review Board approved retrospective case series on women over 18 years with MFPP who received Botox and physical therapy between July 2006 and November 2014. Presence of trigger points and pelvic pain scores were determined by digital palpation of the iliococcygeus, puborectalis, obturator internus, and rectus muscles. Average pelvic pain scores (0-10) reflected an average of the scores obtained from palpation of each muscle. Self-reported improvement in pain was recorded as yes/no.

RESULTS

Fifty women met the inclusion/exclusion criteria. Posttreatment, patients had lower average pelvic pain scores (3.7±4.0 vs. 6.4±1.8, p=0.005), and fewer trigger points (44% vs. 100%, p<0.001). Fifty-eight percent of patients (95% confidence interval, 44-72) noted an improvement in self-reported pain. Patients most likely to report no improvement in pain had chronic bowel disorders, while those most likely to report an improvement in pain had a history of past incontinence sling (p=0.03). Posttreatment complications included: constipation (8%), worsening urinary retention (2%), and urinary tract infection (4%).

CONCLUSIONS

Botox combined with soft tissue myofascial release physical therapy under anesthesia can be effective in treating women with chronic pelvic pain secondary to MFPP.

摘要

目的

通过比较治疗前后的平均骨盆疼痛评分、触发点和患者自我报告的骨盆疼痛,报告联合肉毒杆菌毒素 A(肉毒杆菌毒素)注射和肌筋膜松解物理疗法对肌筋膜骨盆疼痛(MFPP)的影响。次要结果是检查治疗后的并发症,并确定疼痛改善患者与无改善患者之间的人口统计学差异。

材料和方法

这是一项机构审查委员会批准的回顾性病例系列研究,纳入了 2006 年 7 月至 2014 年 11 月期间接受肉毒杆菌毒素和物理治疗的 18 岁以上患有 MFPP 的女性患者。通过触诊髂尾肌、耻骨直肠肌、闭孔内肌和腹直肌来确定触发点和骨盆疼痛评分的存在。平均骨盆疼痛评分(0-10)反映了对每个肌肉触诊获得的评分的平均值。自我报告的疼痛改善情况记录为是/否。

结果

50 名女性符合纳入/排除标准。治疗后,患者的平均骨盆疼痛评分较低(3.7±4.0 对 6.4±1.8,p=0.005),触发点较少(44%对 100%,p<0.001)。58%的患者(95%置信区间,44-72)报告自我报告的疼痛有所改善。最有可能报告疼痛无改善的患者患有慢性肠功能紊乱,而最有可能报告疼痛改善的患者有过去的尿失禁吊带史(p=0.03)。治疗后并发症包括:便秘(8%)、尿潴留恶化(2%)和尿路感染(4%)。

结论

肉毒杆菌毒素联合软组织肌筋膜松解物理疗法在麻醉下可有效治疗由 MFPP 引起的慢性骨盆疼痛的女性。

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