Klaiber H, Genton C, Schreiner W, Keller P J
Department für Frauenheilkunde, Universitätsspital Zürich.
Geburtshilfe Frauenheilkd. 1987 Nov;47(11):817-20. doi: 10.1055/s-2008-1036054.
One of the rare tumors causing virilization are the lipid cell tumors which are mostly located in the ovaries. We report here on a 13 year old girl with virilization due to a lipid cell tumor of the broad ligament. The patient showed increased levels of testosterone, androstenedione and 17 alpha-hydroxyprogesterone while normal values of dehydroepiandrosterone, cortisol, estrogens E1 and E2, and gonadotropins were recorded. The endocrinological and histological pictures, as well as the diagnostic aspects will be discussed.
导致男性化的罕见肿瘤之一是脂质细胞瘤,其大多位于卵巢。我们在此报告一名13岁因阔韧带脂质细胞瘤导致男性化的女孩。患者睾酮、雄烯二酮和17α-羟孕酮水平升高,而脱氢表雄酮、皮质醇、雌激素E1和E2以及促性腺激素值正常。将讨论其内分泌和组织学表现以及诊断方面。