Large retrospective effects, clear differences in animals, and multiple negative randomised controlled trials: this is exactly how it is supposed to work.
作者信息
Zimring James C, Spitalnik Steven L
机构信息
Bloodworks NW Research Institute, Seattle, WA, United States of America.
University of Washington School of Medicine, Department of Laboratory Medicine and Department of Medicine, Division of Hematology, Seattle, WA, United States of America.
出版信息
Blood Transfus. 2017 Mar;15(2):104-106. doi: 10.2450/2017.0307-16.
Abstract
摘要
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本文引用的文献
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Effect of Short-Term vs. Long-Term Blood Storage on Mortality after Transfusion.短期与长期血液储存对输血后死亡率的影响。
N Engl J Med. 2016 Nov 17;375(20):1937-1945. doi: 10.1056/NEJMoa1609014. Epub 2016 Oct 24.
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Effect of Transfusion of Red Blood Cells With Longer vs Shorter Storage Duration on Elevated Blood Lactate Levels in Children With Severe Anemia: The TOTAL Randomized Clinical Trial.红细胞输注储存时间长短对严重贫血儿童血乳酸水平升高的影响：TOTAL 随机临床试验。
JAMA. 2015 Dec 15;314(23):2514-23. doi: 10.1001/jama.2015.13977.
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Effects of red-cell storage duration on patients undergoing cardiac surgery.红细胞储存时长对心脏手术患者的影响。
N Engl J Med. 2015 Apr 9;372(15):1419-29. doi: 10.1056/NEJMoa1414219.
4
Age of transfused blood in critically ill adults.危重症成人输注血液的年龄。
N Engl J Med. 2015 Apr 9;372(15):1410-8. doi: 10.1056/NEJMoa1500704. Epub 2015 Mar 17.
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Effect of fresh red blood cell transfusions on clinical outcomes in premature, very low-birth-weight infants: the ARIPI randomized trial.新鲜红细胞输注对早产儿、极低出生体重儿临床结局的影响：ARIPI 随机试验。
JAMA. 2012 Oct 10;308(14):1443-51. doi: 10.1001/2012.jama.11953.
6
Duration of red-cell storage and complications after cardiac surgery.心脏手术后红细胞储存时间与并发症
N Engl J Med. 2008 Mar 20;358(12):1229-39. doi: 10.1056/NEJMoa070403.
7
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.C3H/HeJ和C57BL/10ScCr小鼠中LPS信号传导缺陷：Tlr4基因的突变
Science. 1998 Dec 11;282(5396):2085-8. doi: 10.1126/science.282.5396.2085.
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