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Quantitation and tissue localization of the cellular retinoic acid-binding protein.

作者信息

Eriksson U, Hansson E, Nordlinder H, Busch C, Sundelin J, Peterson P A

机构信息

Department of Cell Research, Wallenberg Laboratory, University of Uppsala, Sweden.

出版信息

J Cell Physiol. 1987 Dec;133(3):482-90. doi: 10.1002/jcp.1041330308.

DOI:10.1002/jcp.1041330308
PMID:2826496
Abstract

The distribution of the cellular retinoic acid-binding protein (CRABP) in some rat tissues has been determined, and the protein has been localized by immunocytochemical techniques in sections from rat testis. In the testis CRABP was found in the seminiferous tubuli with Sertoli cells and the spermatogonia most intensely stained. All other cells of the germinal epithelium appeared largely devoid of CRABP. By use of an enzyme-linked immunosorbent assay CRABP was quantitatively estimated in several tissues and the highest levels were found in testis and eye. Comparisons of the tissue levels of CRABP and of the cellular retinol-binding protein (CRBP) did not reveal any apparent correlation.

摘要

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