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病例报告:阿哌沙班引起的血小板减少症。

Case report: apixaban-induced thrombocytopenia.

作者信息

Snellgrove Oliver

机构信息

Intensive Care Unit Hornsby Hospital Hornsby New South Wales Australia.

出版信息

Clin Case Rep. 2017 Feb 1;5(3):268-269. doi: 10.1002/ccr3.809. eCollection 2017 Mar.

DOI:10.1002/ccr3.809
PMID:28265388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5331230/
Abstract

Apixaban is a relatively new drug, and its safety profile is still being established. Thrombocytopenia is an uncommon, but life-threatening side effect with no previous published case repots. Clinicians must be aware of this and exercise caution particularly as some studies hint that it may be used in the management of HIT.

摘要

阿哌沙班是一种相对较新的药物,其安全性仍在确定之中。血小板减少症是一种罕见但危及生命的副作用,此前尚无相关病例报道。临床医生必须对此有所了解并谨慎使用,特别是因为一些研究暗示它可能用于治疗肝素诱导的血小板减少症(HIT)。

相似文献

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Case report: apixaban-induced thrombocytopenia.病例报告:阿哌沙班引起的血小板减少症。
Clin Case Rep. 2017 Feb 1;5(3):268-269. doi: 10.1002/ccr3.809. eCollection 2017 Mar.
2
Apixaban as an alternate oral anticoagulant for the management of patients with heparin-induced thrombocytopenia.阿哌沙班作为一种替代口服抗凝剂用于肝素诱导的血小板减少症患者的治疗。
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Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature.阿哌沙班治疗确诊的肝素诱导的血小板减少症:一例病例报告及文献综述
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Apixaban: a novel agent to treat heparin induced thrombocytopenia and to prevent embolism in patient with atrial fibrillation after multiple valve replacement?阿哌沙班:新型药物可治疗肝素诱导的血小板减少症,并预防多次瓣膜置换术后心房颤动患者的栓塞?
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Apixaban therapy in a pregnant woman with heparin-induced thrombocytopenia and venous thromboembolic events caused by congenital antithrombin deficiency: A case report.阿哌沙班治疗一名患有肝素诱导的血小板减少症及先天性抗凝血酶缺乏所致静脉血栓栓塞事件的孕妇:一例报告
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Emerging Role of Direct Oral Anticoagulants in the Management of Heparin-Induced Thrombocytopenia.直接口服抗凝剂在肝素诱导的血小板减少症管理中的新作用。
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Direct-acting oral anticoagulants as emerging treatment options for heparin-induced thrombocytopenia.直接作用口服抗凝剂作为肝素诱导的血小板减少症的新兴治疗选择。
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The Role of Apixaban in the Treatment of Heparin-Induced Thrombocytopenia.阿哌沙班在肝素诱导的血小板减少症治疗中的作用。
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引用本文的文献

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J Clin Med. 2023 Dec 12;12(24):7637. doi: 10.3390/jcm12247637.
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Thrombocytopenia Due to Direct Oral Anticoagulation and Low-Molecular-Weight Heparin.直接口服抗凝药和低分子量肝素所致血小板减少症
Cureus. 2021 Oct 13;13(10):e18757. doi: 10.7759/cureus.18757. eCollection 2021 Oct.
3
2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation.2021年欧洲心律协会心房颤动患者使用非维生素K拮抗剂口服抗凝药实用指南。
Europace. 2021 Oct 9;23(10):1612-1676. doi: 10.1093/europace/euab065.
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Thrombocytopenia: A possible side effect of apixaban.血小板减少症:阿哌沙班的一种可能副作用。
Clin Case Rep. 2019 Nov 21;7(12):2543-2544. doi: 10.1002/ccr3.2532. eCollection 2019 Dec.

本文引用的文献

1
A 7-year case of furosemide-induced immune thrombocytopenia.呋塞米诱导免疫性血小板减少症 7 年病例报告。
Pharmacotherapy. 2013 Jul;33(7):e162-5. doi: 10.1002/phar.1279. Epub 2013 Apr 26.
2
Apixaban versus warfarin in patients with atrial fibrillation.阿哌沙班与华法林用于房颤患者。
N Engl J Med. 2011 Sep 15;365(11):981-92. doi: 10.1056/NEJMoa1107039. Epub 2011 Aug 27.