Rotker Katherine, Vigneswaran Hari, Omil-Lima Danly, Sigman Mark, Hwang Kathleen
Brown University, Providence, RI.
Brown University, Providence, RI.
Urology. 2017 Jun;104:90-96. doi: 10.1016/j.urology.2017.01.041. Epub 2017 Mar 4.
To examine the effect of brief nurse counseling on sperm banking rates among patients prior to initiating chemotherapy.
A retrospective chart review was performed for men aged 18-50 with newly diagnosed cancer, from 1998 to 2003, prior to initiation of chemotherapy. A standardized nursing education session including brief fertility counseling was implemented at one institution in 2008 (Institution A). Rates of sperm banking among patients who received counseling were compared to those without counseling at institution A and to those at institution B where a counseling program was never initiated.
A total of 766 male patients, 402 treated at institution A and 364 at institution B, were included. At institution A, sperm banking rates prior to 2008 were 6.4% and 8.3% after 2008 for those who did not receive counseling. The rate of sperm banking for those patients who did receive counseling was significantly higher at 17.6% (P = .002). The odds of banking increased 2.9 times for those who received counseling compared to those who did not (P = .003). At institution B, where counseling was never initiated, rates of banking remained low before and after 2008. Additional analysis revealed that younger patients and those patients who did not have children were more likely to perform sperm banking.
The rates of sperm banking among cancer patients increased with the receipt of a brief, formalized nurse counseling session prior to initiation of chemotherapy. These findings may validate the use of a formalized fertility counseling prior to initiation of chemotherapy.
研究化疗开始前护士简短咨询对患者精子库保存率的影响。
对1998年至2003年新诊断为癌症、年龄在18 - 50岁且即将开始化疗的男性患者进行回顾性病历审查。2008年在一家机构(机构A)实施了包括简短生育咨询的标准化护理教育课程。将机构A中接受咨询的患者与未接受咨询的患者以及从未启动咨询项目的机构B中的患者的精子库保存率进行比较。
共纳入766名男性患者,其中402名在机构A接受治疗,364名在机构B接受治疗。在机构A,2008年前未接受咨询的患者精子库保存率为6.4%,2008年后为8.3%。接受咨询的患者精子库保存率显著更高,为17.6%(P = 0.002)。与未接受咨询的患者相比,接受咨询的患者进行精子库保存的几率增加了2.9倍(P = 0.003)。在从未启动咨询的机构B,2008年前后精子库保存率一直较低。进一步分析显示,年轻患者和没有孩子的患者更有可能进行精子库保存。
癌症患者在化疗开始前接受简短、规范化的护士咨询后,精子库保存率有所提高。这些发现可能证实了在化疗开始前进行规范化生育咨询的作用。