Yatsushiro Satoshi, Sunohara Saeko, Takizawa Ken, Matsumae Mitsunori, Kajihara Nao, Kuroda Kagayaki
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:3867-3870. doi: 10.1109/EMBC.2016.7591572.
To investigate spatial distribution properties of the cardiac- and respiratory-driven cerebrospinal fluid (CSF) motions in the intracranial space, correlation mapping technique was conducted. Time series of CSF velocity were acquired in 7 healthy subjects of 26±5 years old under by asynchronous 2-dimensional phase contrast (2D-PC) method with 217-msec temporal resolution. The delay time and maximum correlation maps of the cardiac- and respiratory-driven CSF motions demonstrated clear differences in the propagation properties. When the reference region was set at anterior spinal subarachnoid space, the maximum correlation coefficients in the case of 6-sec respiratory period were 0.91±0.05 for cardiac-driven and 0.78±0.08 for respiratory-driven. They were 0.90±0.06 and 0.81±0.06 in the case of 10-sec period. The cardiac- and respiratory CSF motions differently distributed in intracranial space.
为研究颅内空间中心脏驱动和呼吸驱动的脑脊液（CSF）运动的空间分布特性，采用了相关映射技术。通过异步二维相位对比（2D-PC）方法，以217毫秒的时间分辨率，获取了7名年龄在26±5岁的健康受试者的脑脊液速度时间序列。心脏驱动和呼吸驱动的脑脊液运动的延迟时间和最大相关图显示出传播特性的明显差异。当参考区域设定在前脊髓蛛网膜下腔时，在6秒呼吸周期的情况下，心脏驱动的最大相关系数为0.91±0.05，呼吸驱动的为0.78±0.08。在10秒周期的情况下，它们分别为0.90±0.06和0.81±0.06。心脏和呼吸脑脊液运动在颅内空间的分布不同。
