Ravaghi Hamid, Behzadifar Masoud, Behzadifar Meysam, Taheri Mirghaed Masood, Aryankhesal Aidin, Salemi Morteza, Bragazzi Nicola Luigi
Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
Iran J Kidney Dis. 2017 Mar;11(2):90-98.
Chronic kidney disease is a public health problem worldwide that is highly associated with psychological disorders. This study aimed to assess prevalence of depression in hemodialysis patients in Iran.
Relevant studies were identified from the PubMed, ISI Web of Science, Ovid, Scopus, EMBase, and Iranian databases including Magiran, SID, IranMedex, and Irandoc, up to December 2015. The DerSimonian-Laird random effects model was employed to estimate the overall pooled prevalence. Heterogeneity was investigated and subgroup analyses were carried out by sample size and time of study.
Twenty-seven studies on 2822 patients met the inclusion criteria for analysis. The pooled analysis of depressive symptoms in hemodialysis patients in Iran was estimated to be 62% (95% confidence interval, 0.54 to 0.71) with a maximum rate of 95% (95% confidence interval, 0.88 to 1.02) and a minimum rate of 9% (95% confidence interval, 0.02 to 0.16). Statistical heterogeneity was high (I2 = 96.9%).
The results of this study showed that depression is common among dialysis patients in Iran. Early diagnosis and effective treatment of depression can improve quality of life, prognosis, and survival of patients.
慢性肾脏病是一个全球性的公共卫生问题，与心理障碍高度相关。本研究旨在评估伊朗血液透析患者中抑郁症的患病率。
截至2015年12月，从PubMed、ISI科学网、Ovid、Scopus、EMBase以及包括Magiran、SID、IranMedex和Irandoc在内的伊朗数据库中检索相关研究。采用DerSimonian-Laird随机效应模型估计总体合并患病率。对异质性进行了研究，并按样本量和研究时间进行了亚组分析。
27项涉及2822例患者的研究符合纳入分析标准。伊朗血液透析患者抑郁症状的合并分析估计为62%（95%置信区间，0.54至0.71），最高发生率为95%（95%置信区间，0.88至1.02），最低发生率为9%（95%置信区间，0.02至0.16）。统计异质性较高（I2 = 96.9%）。
本研究结果表明，抑郁症在伊朗透析患者中很常见。早期诊断和有效治疗抑郁症可改善患者的生活质量、预后和生存率。
