光学相干弹性成像——组织生物力学中的光学相干断层扫描技术[特邀报告]
Optical coherence elastography - OCT at work in tissue biomechanics [Invited].
作者信息
Larin Kirill V, Sampson David D
机构信息
Department of Biomedical Engineering, University of Houston, 3605 Cullen Blvd., Houston, Texas 77204-5060, USA; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, USA;
Optical + Biomedical Engineering Laboratory, School of Electrical, Electronic & Computer Engineering, The University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia; Centre for Microscopy, Characterisation & Analysis, The University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia;
出版信息
Biomed Opt Express. 2017 Jan 27;8(2):1172-1202. doi: 10.1364/BOE.8.001172. eCollection 2017 Feb 1.
Optical coherence elastography (OCE), as the use of OCT to perform elastography has come to be known, began in 1998, around ten years after the rest of the field of elastography - the use of imaging to deduce mechanical properties of tissues. After a slow start, the maturation of OCT technology in the early to mid 2000s has underpinned a recent acceleration in the field. With more than 20 papers published in 2015, and more than 25 in 2016, OCE is growing fast, but still small compared to the companion fields of cell mechanics research methods, and medical elastography. In this review, we describe the early developments in OCE, and the factors that led to the current acceleration. Much of our attention is on the key recent advances, with a strong emphasis on future prospects, which are exceptionally bright.
光学相干弹性成像技术（OCE），也就是利用光学相干断层扫描（OCT）进行弹性成像的技术，始于1998年，比弹性成像领域的其他技术晚了大约十年，弹性成像领域是利用成像技术推断组织的力学特性。在经历了缓慢的起步阶段后，21世纪初至中期OCT技术的成熟为该领域最近的加速发展奠定了基础。2015年发表了20多篇论文，2016年发表了25多篇论文，OCE发展迅速，但与细胞力学研究方法和医学弹性成像等相关领域相比，规模仍然较小。在这篇综述中，我们描述了OCE的早期发展以及导致当前加速发展的因素。我们的大部分注意力集中在近期的关键进展上，并特别强调了前景异常光明的未来前景。
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