Jha Ashish Kumar, Goenka Mahesh Kumar, Goenka Usha
Department of Gastroenterology, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, 800 014, India.
Institute of Gastrosciences, Apollo Gleneagles Hospital, Canal Circular Road, Kolkata, 700 054, India.
Indian J Gastroenterol. 2017 Mar;36(2):131-136. doi: 10.1007/s12664-017-0733-9. Epub 2017 Mar 8.
There is a wide variation in the clinical presentation of chronic pancreatitis (CP) in the different parts of India. Data regarding the clinical profile of CP from eastern India are scarce. We describe the clinical and demographic profiles of patients with CP in eastern India. Consecutive patients were evaluated for the clinical presentation, etiology and complication of CP. One hundred and thirty-nine patients with CP (mean age 39.57±14.88 years; M/F 3.48:1) were included. Idiopathic CP (50.35%) was the most common etiology followed by alcohol (33.81%); 68.34% had calcific CP and 31.65% had noncalcific CP. The median duration of symptoms was 24 (1-240) months. Pain was the most common symptom, being present in 93.52% of the patients. Diabetes, steatorrhea and pseudocyst were present in 45.32%, 14.38% and 7.19% of the cases, respectively. Moderate to severe anemia was revealed in 16.53% of the patients. Benign biliary stricture was diagnosed in 19.42% of the cases (symptomatic in 6.47%). The common radiological findings were the following: pancreatic calculi (68.34%), dilated pancreatic duct (PD) (58.99%), parenchymal atrophy (25.89%) and PD stricture (23.74%). In our center, idiopathic CP followed by alcoholic CP was the most frequent form of CP. Tropical CP was distinctly uncommon.
慢性胰腺炎(CP)在印度不同地区的临床表现存在很大差异。来自印度东部的关于CP临床特征的数据很少。我们描述了印度东部CP患者的临床和人口统计学特征。对连续的患者进行了CP临床表现、病因和并发症的评估。纳入了139例CP患者(平均年龄39.57±14.88岁;男/女为3.48:1)。特发性CP(50.35%)是最常见的病因,其次是酒精性(33.81%);68.34%为钙化性CP,31.65%为非钙化性CP。症状的中位持续时间为24(1 - 240)个月。疼痛是最常见的症状,93.52%的患者有疼痛症状。糖尿病、脂肪泻和假性囊肿分别出现在45.32%、14.38%和7.19%的病例中。16.53%的患者有中度至重度贫血。19.42%的病例诊断为良性胆管狭窄(6.47%有症状)。常见的影像学表现如下:胰腺结石(68.34%)、胰管(PD)扩张(58.99%)、实质萎缩(25.89%)和PD狭窄(23.74%)。在我们中心,特发性CP其次是酒精性CP是CP最常见的形式。热带性CP明显不常见。