El Meddeb Hamrouni A, Chehata Jebsi M, Kanoun S, Rancoule C, Guy J B, Magne N, Bouaouina N
Department of Radiation Oncology, Hospital of Farhat Hached, Susah, Tunisia.
Institut de Cancérologie Lucien-Neuwirth, Department of Radiation Oncology, 108 bis, Avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez, France.
Gulf J Oncolog. 2017 Jan;1(23):63-66.
The purpose of this article is to report a new case of a probably radio-induced bilateral breast cancer occurred after prophylactic bilateral pulmonary irradiation in the treatment of osteosarcoma. A 42-year-old woman, treated at the age of 12 years for osteosarcoma at the right lower limb with chemotherapy (methotrexate, adriamycin and cisplatin) followed by non-conservative surgery and adjuvant radiotherapy. Eighteen years after, she developed her first breast cancer, and five years later, her second contralateral breast cancer. The patient was treated for her two non-metastatic cancers and is currently in complete remission. This publication adds to several previous publications the very probable effect of ionizing radiation in the occurrence of secondary cancers.
