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肝门部不可切除原发性癌的手术入路

Surgical approaches for unresectable primary carcinoma of the hepatic hilus.

作者信息

Lygidakis N J, van der Heyde M N, van Dongen R J, Kromhout J G, Tytgat G N, Huibregtse K

机构信息

University of Amsterdam, Department of Surgery, Academic Medical Center, The Netherlands.

出版信息

Surg Gynecol Obstet. 1988 Feb;166(2):107-14.

PMID:2827329
Abstract

Thirteen patients with proximal malignant obstruction of the biliary tract secondary to primary cholangiocarcinoma are presented. Seven of these patients had bilateral involvement of the major vessels of the porta hepatis, and 12 had bilateral involvement of the main hepatic ducts up to the level of segmental bifurcation. Resection of the tumor was carried out in all of the patients. Extensive resection of the liver with resection of the regional vascular structures was done in six. Another six underwent resection of the liver without resection of the regional vascular structures. The remaining patient underwent resection of the tumor and of the regional revascular structures alone. Vascular resection included resection and reconstruction of both the portal vein and hepatic artery in four patients or only of the portal vein in three. Biliary drainage was carried out by intrahepatic cholangiojejunostomies between segmental hepatic ducts and a Roux-en-Y loop. Two patients died and ten are alive. The quality of postoperative life is satisfactory and the patients are free of sequelae and symptoms secondary to operation or disease. This approach is recommended for the management of a number of patients with bilateral vascular or biliary involvement secondary to primary cholangiocarcinoma of the porta hepatis. For those patients, this approach offers a promising alternative.

摘要

本文报告了13例因原发性胆管癌继发近端恶性胆道梗阻的患者。其中7例患者肝门部主要血管双侧受累,12例患者主肝管双侧受累直至肝段分叉水平。所有患者均接受了肿瘤切除。6例患者进行了广泛的肝脏切除并切除了区域血管结构。另外6例患者进行了肝脏切除但未切除区域血管结构。其余1例患者仅进行了肿瘤及区域血管重建结构的切除。血管切除包括4例患者同时切除并重建门静脉和肝动脉,3例患者仅切除门静脉。通过肝段肝管与Roux-en-Y袢之间的肝内胆管空肠吻合术进行胆道引流。2例患者死亡,10例存活。术后生活质量令人满意,患者无手术或疾病继发的后遗症和症状。对于许多因肝门部原发性胆管癌继发双侧血管或胆管受累的患者,推荐采用这种方法。对于这些患者,这种方法提供了一种有前景的选择。

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