Reusch C, Reiter I
Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1987;15(3):305-10.
Between May 1982 and September 1986 13 dogs with leishmaniosis received inpatient treatment with Pentostam at the I. Medical Department of the Veterinary Faculty, University of Munich. Predominant clinical signs of all animals were alterations of the skin and hair coat and additionally they showed a reduced general condition (4 dogs), loss of weight (3 dogs), diarrhea (5 dogs) and pain during movements. In the blood samples taken prior treatment in 9 dogs there was an increased total protein concentration. 5 dogs had changes in the red and 4 dogs in the white blood count. Thrombocytopenia occurred in 6 dogs. Leishmaniosis was diagnosed clinically and serologically (IFAT). Na-Stibogluconate (Pentostam) was used for the treatment at a dosage of 10 or 20 mg/kg on 10 or 14 consecutive days. Two dogs died during an early stage of therapy. 6 dogs were discharged as clinically cured after a single or repeated treatment course(s).
1982年5月至1986年9月期间，13只患有利什曼病的犬在慕尼黑大学兽医学院第一内科接受了喷他脒住院治疗。所有动物的主要临床症状为皮肤和毛发改变，此外还表现出一般状况下降（4只犬）、体重减轻（3只犬）、腹泻（5只犬）以及运动时疼痛。在9只犬治疗前采集的血液样本中，总蛋白浓度升高。5只犬的红细胞计数有变化，4只犬的白细胞计数有变化。6只犬出现血小板减少症。利什曼病通过临床和血清学（间接荧光抗体试验）诊断。使用葡糖酸锑钠（喷他脒）进行治疗，剂量为10或20mg/kg，连续10或14天。2只犬在治疗早期死亡。6只犬在接受单次或重复治疗疗程后临床治愈出院。
