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曼谷泰国青少年初潮年龄过早的相关因素:一项横断面研究。

Factors associated with early age at menarche among Thai adolescents in Bangkok: A cross-sectional study.

作者信息

Noipayak Pongsak, Rawdaree Petch, Supawattanabodee Busaba, Manusirivitthaya Sumonmal

机构信息

Department of Pediatrics, Faculty of Medicine, Vajira Hospital, Samsean Road, Dusit District, Bangkok, 10300, Thailand.

Department of Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand.

出版信息

BMC Womens Health. 2017 Mar 9;17(1):16. doi: 10.1186/s12905-017-0371-5.

Abstract

BACKGROUND

The age at menarche in the Thai population has not been determined since 1997. This study recruited adolescents in Bangkok Metropolis to determine the age at menarche and its associations with health and socioeconomic status.

METHODS

This cross-sectional study used a two-step stratified sampling strategy to recruit 1,020 female students, aged 10-16 years, from schools in Dusit district, Bangkok, Thailand. Self-reported data on age at menarche and social determinants of health were collected from participants and their parents. A trained research nurse collected anthropometric data.

RESULTS

Mean age at menarche was 11.8 ± 1.0 years, and age at menarche was significantly correlated with year of birth (r = -0.4, p < 0.001). Students from schools that are part of Bangkok Metropolis had the lowest mean age at menarche. Participants born in 2000-2003 having their first period at < 11.8 years numbered 5.5 times (95% CI: 3.80-8.18) and 5.0 times (95% CI: 3.6-8.0) greater than those born in 1997-1999 by univariate and multivariate analysis, respectively. Year of birth significantly associated with age at menarche in univariate and multivariate analysis (p = 0.001).

CONCLUSION

The mean age at menarche among female adolescents in Bangkok Metropolis was occurring earlier and was inversely associated with year of birth in this cohort. Only year of birth were associated with age at menarche in the multivariate regression models to adjust for potential confounders.

摘要

背景

自1997年以来,泰国人群的初潮年龄尚未确定。本研究招募了曼谷都会区的青少年,以确定初潮年龄及其与健康和社会经济地位的关联。

方法

这项横断面研究采用两步分层抽样策略,从泰国曼谷杜西地区的学校招募了1020名10 - 16岁的女学生。从参与者及其父母那里收集了关于初潮年龄和健康社会决定因素的自我报告数据。一名经过培训的研究护士收集了人体测量数据。

结果

初潮的平均年龄为11.8±1.0岁,初潮年龄与出生年份显著相关(r = -0.4,p < 0.001)。属于曼谷都会区学校的学生初潮平均年龄最低。单因素和多因素分析显示,2000 - 2003年出生且初潮年龄小于11.8岁的参与者分别是1997 - 1999年出生者的5.5倍(95%置信区间:3.80 - 8.18)和5.0倍(95%置信区间:3.6 - 8.0)。在单因素和多因素分析中,出生年份与初潮年龄显著相关(p = 0.001)。

结论

曼谷都会区女性青少年的初潮平均年龄出现得更早,且与该队列中的出生年份呈负相关。在多变量回归模型中,为调整潜在混杂因素,只有出生年份与初潮年龄相关。

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Age at menarche in Thai girls.泰国女孩的初潮年龄。
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本文引用的文献

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Control of puberty: genetics, endocrinology, and environment.青春期的调控:遗传学、内分泌学和环境。
Curr Opin Endocrinol Diabetes Obes. 2013 Feb;20(1):62-8. doi: 10.1097/MED.0b013e32835b7ec7.
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Parental age at childbirth and age of menarche in the offspring.生育时父母的年龄与子女的初潮年龄。
Hum Reprod. 2010 Mar;25(3):799-804. doi: 10.1093/humrep/dep473. Epub 2010 Jan 19.

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