孕期出现黄素囊肿伴母体男性化及血清睾酮升高。

Theca lutein cysts with maternal virilization and elevated serum testosterone in pregnancy.

作者信息

Ito M, Tohya T, Yoshimura T, Matsui K, Fujisaki S, Okamura H

机构信息

Department of Obstetrics and Gynecology, Kumamoto University Medical School, Japan.

出版信息

Acta Obstet Gynecol Scand. 1987;66(6):565-6. doi: 10.3109/00016348709015737.

DOI:10.3109/00016348709015737

PMID:2827428

Abstract

A clinicopathological study was performed on a pregnant patient with bilateral multiple ovarian cysts, who presented with pre-eclampsia, marked virilization and exceedingly high levels of serum testosterone. The female fetus showed no evidence of virilization. Microscopic examination of the ovaries revealed theca lutein cysts with granulosa cells which showed the existence of testosterone by immunoperoxidase staining.

摘要

对一名患有双侧多发性卵巢囊肿的孕妇进行了临床病理研究，该孕妇出现先兆子痫、明显的男性化以及血清睾酮水平极高的情况。女性胎儿未显示男性化迹象。卵巢的显微镜检查发现了卵泡膜黄素囊肿，其中的颗粒细胞经免疫过氧化物酶染色显示存在睾酮。