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具有男性化表现的卵巢卵泡膜细胞瘤。

Ovarian thecoma with virilizing manifestations.

作者信息

Lee Mun-Hwi, Moon Young-Jin, Ha Chang-Won, Hoh Jeong-Kyu

机构信息

Department of Obstetric and Gynecology, Halla General Hospital, Jeju, Korea.

出版信息

Yonsei Med J. 2009 Feb 28;50(1):169-73. doi: 10.3349/ymj.2009.50.1.169. Epub 2009 Feb 24.

DOI:10.3349/ymj.2009.50.1.169
PMID:19259367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2649854/
Abstract

A 29-year-old woman presented with secondary amenorrhea, primary infertility, and virilization, which had developed over the past 2 years was suspected to have a virilizing tumor at her left ovary. Her serum testosterone level was markedly elevated (380 ng/dL). Left salpingoophorectomy was performed, and histopathological examination revealed a thecoma of the left ovary. The postoperative serum testosterone level returned to 65 ng/dL. The patient did not have regression of virilism soon. However, the patient had a normal menstruation 29 days after surgery and gave birth to a baby 13 months after surgery.

摘要

一名29岁女性出现继发性闭经、原发性不孕和男性化症状，这些症状在过去2年中逐渐出现，怀疑左卵巢有男性化肿瘤。她的血清睾酮水平显著升高（380 ng/dL）。进行了左侧输卵管卵巢切除术，组织病理学检查显示为左卵巢卵泡膜细胞瘤。术后血清睾酮水平恢复至65 ng/dL。患者的男性化症状并未很快消退。然而，患者术后29天月经恢复正常，术后13个月分娩。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/ebf363662792/ymj-50-169-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/a8566d16fd39/ymj-50-169-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/e8e2cf24cc68/ymj-50-169-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/411cb5c3ff4c/ymj-50-169-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/ebf363662792/ymj-50-169-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/a8566d16fd39/ymj-50-169-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/e8e2cf24cc68/ymj-50-169-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/411cb5c3ff4c/ymj-50-169-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b5f/2649854/ebf363662792/ymj-50-169-g004.jpg

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本文引用的文献

1
Ovarian thecoma with androgenic manifestations in a postmenopausal woman.一名绝经后女性出现具有雄激素表现的卵巢卵泡膜细胞瘤。
Gynecol Endocrinol. 2006 Jul;22(7):405-8. doi: 10.1080/09513590600842539.
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[Endocrine-active tumors of the ovary].[卵巢内分泌活性肿瘤]
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Thecoma with associated virilization.伴有男性化的卵泡膜细胞瘤。
Am J Obstet Gynecol. 1959 Oct;78:722-9. doi: 10.1016/s0002-9378(16)36569-3.
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[Clinical analysis of 74 cases with ovarian thecoma].74例卵巢卵泡膜细胞瘤临床分析
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A prospective study of the prevalence of clear-cut endocrine disorders and polycystic ovaries in 350 patients presenting with hirsutism or androgenic alopecia.一项针对350例多毛症或雄激素性脱发患者的明确内分泌疾病和多囊卵巢患病率的前瞻性研究。
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