Banding analysis of three primary cancers.

Chromosomes of a breast cancer and two colonic cancers were studied with banding methods. An intracystic papillary carcinoma of breast had the following constitution: 46, XX, -1, +3, -20, +i(1q), +i(1q), +t(1;20)(p13;p13). The second tumor, a well-differentiated adenocarcinoma of the colon had several autosomal trisomies and del(3)(p14). There was karyotype stability in both tumors. The third tumor, an undifferentiated colonic cancer, had a pseudodiploid stemline, namely 46, XX, -1, +(1q), and four sidelines with additional numerical changes.