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未累及阴蒂、尿道或肛门的鳞状细胞外阴癌的手术治疗

Surgical management of squamous cell vulvar cancer without clitoris, urethra or anus involvement.

作者信息

Kaban Alpaslan, Kaban Işık, Afşar Selim

机构信息

University of Istanbul, Istanbul Faculty of Medicine, Gynecologic Oncology Department, Istanbul, Turkey.

Istanbul Education & Research Hospital, Istanbul, Turkey.

出版信息

Gynecol Oncol Rep. 2017 Feb 10;20:41-46. doi: 10.1016/j.gore.2017.02.004. eCollection 2017 May.

DOI:10.1016/j.gore.2017.02.004
PMID:28275696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5331156/
Abstract

Vulvar cancers, which constitute 5% of all gynecologic cancers, are the fourth most common female genital cancers, preceded by uterine, ovarian and cervical cancers. The treatment methods employed for vulvar cancers have changed over the years, with previously applied radical surgical approaches, such as en bloc resection, being gradually suspended in favor of treatment approaches that require dissection of less tissue. While the removal of less tissue, which today's approaches have focused on, prevents morbidity, this method seems to result in higher risks of recurrence. It is therefore important that the balance between preventing the recurrence of the disease and forefending against postoperative complications and vulvar deformity be properly understood. As a working assumption, if patients with vulvar cancer are diagnosed at an early stage, properly evaluated and administered appropriate treatment, the most positive results can be obtained. This paper aims to highlight this assumption and demonstrate, through the provision of actual data, how to plan the treatment approach for patients who are diagnosed early. Statements extracted from the National Comprehensive Cancer Network (NCCN) Guidelines Version 1.2016 Sub-Committees on vulvar squamous cell carcinoma and articles by the European Society of Gynaecological Oncology (ESGO) regarding Vulvar Cancer Recommendations were used to obtain updated information.

摘要

外阴癌占所有妇科癌症的5%,是第四大常见的女性生殖系统癌症,排在子宫癌、卵巢癌和宫颈癌之后。多年来,外阴癌的治疗方法发生了变化,以前采用的根治性手术方法,如整块切除,逐渐被摒弃,转而采用需要切除更少组织的治疗方法。虽然如今的治疗方法侧重于切除更少的组织,这可以预防并发症,但这种方法似乎会导致更高的复发风险。因此,正确理解预防疾病复发与预防术后并发症和外阴畸形之间的平衡非常重要。作为一个可行的假设,如果外阴癌患者在早期被诊断出来,经过适当评估并接受适当治疗,就能获得最理想的结果。本文旨在强调这一假设,并通过提供实际数据,展示如何为早期诊断的患者规划治疗方案。从《美国国立综合癌症网络(NCCN)指南》2016年第1版外阴鳞状细胞癌小组委员会以及欧洲妇科肿瘤学会(ESGO)关于外阴癌建议的文章中提取的陈述,用于获取最新信息。

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本文引用的文献

1
Sentinel lymph node biopsy in vulvar cancer: Systematic review, meta-analysis and guideline recommendations.外阴癌前哨淋巴结活检:系统评价、荟萃分析及指南推荐
Gynecol Oncol. 2015 May;137(2):351-61. doi: 10.1016/j.ygyno.2015.02.014. Epub 2015 Feb 20.
2
An alternative way to measure the depth of invasion of vulvar squamous cell carcinoma in relation to prognosis.一种评估外阴鳞癌侵袭深度与预后相关性的替代方法。
Mod Pathol. 2015 Feb;28(2):295-302. doi: 10.1038/modpathol.2014.103. Epub 2014 Sep 5.
3
Use of the Sentinel Lymph Node Technique Compared to Complete Inguino-femoral Lymph Node Removal in Patients with Invasive Vulvar Cancer in Germany.
靶向醛脱氢酶以消除妇科恶性肿瘤中的癌症干细胞
Cancers (Basel). 2020 Apr 13;12(4):961. doi: 10.3390/cancers12040961.
4
Vulvar cancer in Iran: Retrospective study over 20 years (1998-2018).伊朗的外阴癌:20年(1998 - 2018年)回顾性研究
J Family Med Prim Care. 2019 Apr;8(4):1465-1469. doi: 10.4103/jfmpc.jfmpc_145_19.
5
Acquired widespread lymphangiectasia mimicking immunobullous disease: A case report.获得性广泛淋巴管扩张症酷似免疫性大疱性疾病:一例报告。
SAGE Open Med Case Rep. 2018 Oct 9;6:2050313X18802137. doi: 10.1177/2050313X18802137. eCollection 2018.
德国浸润性外阴癌患者中前哨淋巴结技术与腹股沟-股淋巴结完全切除术的应用比较
Geburtshilfe Frauenheilkd. 2013 Feb;73(2):142-147. doi: 10.1055/s-0032-1328133.
4
Lymph node count at inguinofemoral lymphadenectomy and groin recurrences in vulvar cancer.腹股沟淋巴结清扫术时的淋巴结计数与外阴癌的腹股沟复发。
Int J Gynecol Cancer. 2014 May;24(4):773-8. doi: 10.1097/IGC.0000000000000125.
5
Cancer statistics, 2014.癌症统计数据,2014 年。
CA Cancer J Clin. 2014 Jan-Feb;64(1):9-29. doi: 10.3322/caac.21208. Epub 2014 Jan 7.
6
Malignant melanoma of the urethra: a rare histologic subdivision of vulvar cancer with a poor prognosis.尿道恶性黑色素瘤:一种罕见的外阴癌组织学亚型,预后较差。
Case Rep Obstet Gynecol. 2012;2012:385175. doi: 10.1155/2012/385175. Epub 2012 Dec 20.
7
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J Clin Oncol. 2012 Nov 1;30(31):3786-91. doi: 10.1200/JCO.2011.41.2528. Epub 2012 Jul 2.
8
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Hematol Oncol Clin North Am. 2012 Feb;26(1):45-62. doi: 10.1016/j.hoc.2011.10.006.
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Am J Obstet Gynecol. 2011 Jun;204(6):466-78. doi: 10.1016/j.ajog.2011.03.008.
10
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Lancet Oncol. 2010 Jul;11(7):646-52. doi: 10.1016/S1470-2045(10)70104-2. Epub 2010 May 25.