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尿道恶性黑色素瘤:一种罕见的外阴癌组织学亚型,预后较差。

Malignant melanoma of the urethra: a rare histologic subdivision of vulvar cancer with a poor prognosis.

作者信息

Günther Veronika, Alkatout I, Lez C, Altarac S, Fures R, Cupic H, Persec Z, Hrgovic Z, Mundhenke C

机构信息

Department of Gynaecology and Obstetrics, University of Kiel, 24105 Kiel, Germany.

出版信息

Case Rep Obstet Gynecol. 2012;2012:385175. doi: 10.1155/2012/385175. Epub 2012 Dec 20.

DOI:10.1155/2012/385175
PMID:23320214
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3539382/
Abstract

Malignant melanoma of the urethra is a rare tumour that is difficult to diagnose and treat, resulting in a poor prognosis. In this paper, we present the case of a 65-year-old woman who was referred to a gynaecologist because of a urethral mass that mimicked a caruncle. The tumour was removed by local excision, and a pathological analysis revealed a malignant melanoma. Distal urethrectomy was performed after three months with no evidence of residual tumour. There was no evidence of disease at a six-year followup. In this paper, we compare the epidemiology, treatment, staging, and prognosis of vulvar cancer in general to malignant melanoma of the vulva in particular.

摘要

尿道恶性黑色素瘤是一种罕见肿瘤,难以诊断和治疗,预后较差。在本文中,我们报告了一例65岁女性病例,该患者因尿道肿物疑似小阜而被转诊至妇科医生处。通过局部切除将肿瘤切除,病理分析显示为恶性黑色素瘤。三个月后进行了远端尿道切除术,未发现残留肿瘤迹象。六年随访时无疾病迹象。在本文中,我们总体比较了外阴癌尤其是外阴恶性黑色素瘤的流行病学、治疗、分期和预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/991535d52fdd/CRIM.OBGYN2012-385175.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/889c656f358f/CRIM.OBGYN2012-385175.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/3f2a5533a4cb/CRIM.OBGYN2012-385175.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/991535d52fdd/CRIM.OBGYN2012-385175.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/889c656f358f/CRIM.OBGYN2012-385175.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/3f2a5533a4cb/CRIM.OBGYN2012-385175.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/508d/3539382/991535d52fdd/CRIM.OBGYN2012-385175.003.jpg

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Primary mucosal melanomas: a comprehensive review.原发性黏膜黑色素瘤:一项全面综述。
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Carcinosarcoma of female urethra with melanocytic differentiation.伴有黑素细胞分化的女性尿道癌肉瘤
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CTLA-4 blockade: therapeutic potential in cancer treatments.CTLA-4 阻断:癌症治疗中的治疗潜力。
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An Overview of Vulvar Cancer: A Single-Center Study from Northeast India.外阴癌概述:来自印度东北部的一项单中心研究
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Primary malignant melanoma of the female urethra: Report of a rare neoplasm of the urinary tract.女性尿道原发性恶性黑色素瘤:一例罕见的泌尿道肿瘤报告。
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Gynecol Oncol Rep. 2017 Feb 10;20:41-46. doi: 10.1016/j.gore.2017.02.004. eCollection 2017 May.
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