Vuik F E R, Koehestanie P, Herbers A H E, Terhaar Sive Droste J S
Department of Gastroenetrology, Jeroen Bosch Hospital, Den Bosch, the Netherlands.
Neth J Med. 2017 Mar;75(2):81-83.
Metamizole can be used in both short- and long-term pain relief therapies and has a relatively favourable safety profile compared with classic NSAIDs. Metamizole is also infamous because of its potential fatal adverse drug reaction, agranulocytosis. Although this risk varies, it is estimated to occur in less than one million metamizole prescriptions. We describe a case of a 68-year-old patient who developed leukopenia after using metamizole.
安乃近可用于短期和长期的疼痛缓解治疗,与传统非甾体抗炎药相比,其安全性相对较好。然而,安乃近也因其潜在的致命药物不良反应——粒细胞缺乏症而声名狼藉。尽管这种风险各不相同,但据估计,在不到一百万张安乃近处方中会出现这种情况。我们描述了一例68岁患者在使用安乃近后出现白细胞减少症的病例。