Mayer S, Kündiger T, Schrader H
Medizinische Klinik und Funktionsdiagnostik, Endoskopie, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland.
Medizinische Klinik, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland.
Internist (Berl). 2017 Jul;58(7):740-744. doi: 10.1007/s00108-017-0207-2.
We report on a 77-year-old male patient with neutropenic fever as a result of a newly diagnosed agranulocytosis. The patient was taking metamizole, which is a well known cause of agranulocytosis. The diagnosis of metamizole-induced agranulocytosis as an underestimated side-effect of metamizole could be confirmed by a bone marrow biopsy. The bone marrow and the blood count recovered completely after stopping the therapy with metamizole and administration of granulocyte colony-stimulating factor (G-CSF).
我们报告了一例77岁男性患者，因新诊断的粒细胞缺乏症而出现中性粒细胞减少性发热。该患者正在服用安乃近，这是粒细胞缺乏症的一个众所周知的病因。通过骨髓活检可以证实安乃近诱导的粒细胞缺乏症是安乃近一种被低估的副作用。停用安乃近并给予粒细胞集落刺激因子（G-CSF）治疗后，骨髓和血细胞计数完全恢复。
