Hendrickson Marissa A, Zaremba Jennifer, Wey Andrew R, Gaillard Philippe R, Kharbanda Anupam B
Pediatr Emerg Care. 2018 Apr;34(4):227-232. doi: 10.1097/PEC.0000000000001070.
Guidelines recommend oral rehydration therapy (ORT) and avoidance of laboratory tests and intravenous fluids for mild to moderate dehydration in children with gastroenteritis; oral ondansetron has been shown to be an effective adjunct.
The aim of this study was to determine if a triage-based, nurse-initiated protocol for early provision of ondansetron and ORT could safely improve the care of pediatric emergency department (ED) patients with symptoms of gastroenteritis.
This study evaluated a protocol prompting triage nurses to assess dehydration in gastroenteritis patients and initiate ondansetron and ORT if indicated. Otherwise well patients aged 6 months to 5 years with symptoms of gastroenteritis were eligible. Prospective postintervention data were compared with retrospective, preintervention control subjects.
One hundred twenty-eight (81 postintervention and 47 preintervention) patients were analyzed; average age was 2.1 years. Ondansetron use increased from 36% to 75% (P < 0.001). Time to ondansetron decreased from 60 minutes to 30 minutes (P = 0.004). Documented ORT increased from 51% to 100% (P < 0.001). Blood testing decreased from 37% to 21% (P = 0.007); intravenous fluid decreased from 23% to 9% (P = 0.03). Fifty-two percent of postintervention patients were discharged with prescriptions for ondansetron. There were no significant changes in ED length of stay, admissions, or unscheduled return to care.
A triage nurse-initiated protocol for early use of oral ondansetron and ORT in children with evidence of gastroenteritis is associated with increased and earlier use of ondansetron and ORT and decreased use of IV fluids and blood testing without lengthening ED stays or increasing rates of admission or unscheduled return to care.
指南推荐对患有肠胃炎的儿童轻至中度脱水采用口服补液疗法(ORT),避免进行实验室检查和静脉输液;已证明口服昂丹司琼是一种有效的辅助治疗方法。
本研究的目的是确定基于分诊的、由护士发起的早期提供昂丹司琼和ORT的方案是否能安全改善儿科急诊科(ED)有肠胃炎症状患者的护理。
本研究评估了一项促使分诊护士评估肠胃炎患者脱水情况并在有指征时启动昂丹司琼和ORT的方案。否则,年龄在6个月至5岁、有肠胃炎症状的健康患者符合条件。将干预后的前瞻性数据与回顾性的干预前对照对象进行比较。
分析了128例患者(干预后81例,干预前47例);平均年龄为2.1岁。昂丹司琼的使用从36%增加到75%(P<0.001)。给予昂丹司琼的时间从60分钟减少到30分钟(P = 0.004)。记录在案的ORT从51%增加到100%(P<0.001)。血液检查从37%减少到21%(P = 0.007);静脉输液从23%减少到9%(P = 0.03)。52%的干预后患者出院时开具了昂丹司琼处方。急诊科住院时间、住院率或非计划复诊率无显著变化。
对于有肠胃炎证据的儿童,由分诊护士发起的早期使用口服昂丹司琼和ORT的方案与昂丹司琼和ORT的使用增加及使用时间提前、静脉输液和血液检查的使用减少相关,且不会延长急诊科住院时间或增加住院率或非计划复诊率。