Tomimoto H, Kamo H, Kameyama M, McGeer P L, Kimura H
Department of Neurology, Faculty of Medicine, Kyoto University, Japan.
Brain Res. 1987 Nov 10;425(2):248-55. doi: 10.1016/0006-8993(87)90507-5.
Descending pathways from the mediobasal forebrain were studied in the rat by injecting anterograde axonal tracer Phaseolus vulgaris leucoagglutinin into the substantia innominata and diagonal band of Broca. From both areas, positive fibers which varied in density were observed in the mediodorsal and ventral parts of the ventroposterior and ventromedial thalamic nuclei, the lateral habenula, the stria medullaris, the lateral hypothalamus and the ventral tegmental area. This descending complex appeared predominantly course through the medial forebrain bundle from which positive fibers ramified into the fasciculus thalamicus to distribute in the thalamic nuclei. A minor descending pathway through the stria medullaris was also noted which terminated in the lateral habenula and the mediodorsal thalamic nucleus. An obvious difference in terminal distribution in the medial habenula, mediodorsal thalamic nucleus and pons could be observed following substantia innominata or diagonal band injection.
通过将顺行轴突示踪剂菜豆白细胞凝集素注射到大鼠无名质和布罗卡斜带，对来自中基底前脑的下行通路进行了研究。在两个区域中，在腹后核和腹内侧丘脑核的内侧和腹侧部分、外侧缰核、髓纹、外侧下丘脑和腹侧被盖区观察到密度不同的阳性纤维。这种下行复合体主要通过内侧前脑束走行，阳性纤维从内侧前脑束分支进入丘脑束，分布于丘脑核。还注意到一条通过髓纹的次要下行通路，其终止于外侧缰核和背内侧丘脑核。在注射无名质或斜带后，可以观察到内侧缰核、背内侧丘脑核和脑桥终末分布的明显差异。
