Jani Nor Akmalazura, Sirat Hasnah Mohd, Ahmad Farediah, Mohamad Ali Nor Azah, Jamil Mailina
a Faculty of Science, Department of Chemistry , Universiti Teknologi Malaysia , Skudai , Malaysia.
b Faculty of Applied Science , Universiti Teknologi MARA Cawangan Negeri Sembilan , Kuala Pilah , Malaysia.
Nat Prod Res. 2017 Dec;31(23):2793-2796. doi: 10.1080/14786419.2017.1294172. Epub 2017 Feb 24.
Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17.4%), 1-epi-cubenol (11.8%), cyperotundone (9.0%), cis-cadin-4-en-7-ol (7.7%), τ-cadinol (7.1%) and α-cadinol (7.1%) were the principle constituents in the stem oil, whereas β-caryophyllene (18.9%), bicyclogermacrene (18.6%) and trans-muurola-4(14),5-diene (9.8%) were the major constituents in the leaf oil. Among the identified constituents, three constituents namely 7-epi-α-selinene, junenol and cis-cadin-4-en-7-ol have not been found previously from Neolitsea oils. The stem and leaf oils were screened for their α-glucosidase inhibitory and antibacterial activities. Both oils displayed potential α-glucosidase inhibitory activity, while the stem oil possessed weak antibacterial activity against Bacillus subtilis.
对采自马来西亚吉辇山的 Kedah 新木姜子（Neolitsea kedahense Gamble）新鲜茎叶进行水蒸馏，随后进行气相色谱 - 火焰离子化检测（GC - FID）和气相色谱 - 质谱联用分析（GC - MS），结果显示共检测到 47 种成分，其中茎中有 28 种（86.4%），叶中有 31 种（96.4%）。δ-杜松烯（17.4%）、1-表古巴醇（11.8%）、香附子烯二酮（9.0%）、顺式-杜松-4-烯-7-醇（7.7%）、τ-杜松醇（7.1%）和α-杜松醇（7.1%）是茎油中的主要成分，而β-石竹烯（18.9%）、双环大根香叶烯（18.6%）和反式-穆罗-4(14),5-二烯（9.8%）是叶油中的主要成分。在已鉴定的成分中，7-表-α-芹子烯、珠树醇和顺式-杜松-4-烯-7-醇这三种成分此前在新木姜子属植物油中未曾发现。对茎油和叶油进行了α-葡萄糖苷酶抑制活性和抗菌活性筛选。两种油均表现出潜在的α-葡萄糖苷酶抑制活性，而茎油对枯草芽孢杆菌具有较弱的抗菌活性。
