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台湾锐叶木姜子叶油和枝油的成分及抗菌活性

Composition and antimicrobial activity of the leaf and twig oils of Litsea acutivena from Taiwan.

作者信息

Ho Chen-Lung, Liao Pei-Chun, Wang Eugene I-Chen, Su Yu-Chang

机构信息

Department of Forestry, National Chung Hsing University, 250 Kuo Kuang Rd., Taichung, Taiwan 402.

出版信息

Nat Prod Commun. 2011 Nov;6(11):1755-8.

Abstract

The chemical composition, and antimicrobial and anti-wood-decay fungal activities of the essential oils isolated from the leaves and twigs of Litsea acutivena of Taiwan were investigated. The essential oils from the fresh leaves and twigs were isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Ninety-five and fifty-two compounds were identified in the leaf and twig oils, respectively. The main components of the leaf oil were gamma-patchoulene (11.0%), delta-cadinene (6.3%), trans-muurola-3,5-diene (5.9%), and beta-selinene (5.3%), whereas the main components of the twig oil were tau-cadinol (13.1%), beta-selinene (9.6%), trans-beta-ocimene (6.2%) and alpha-cadinol (7.7%). Bioactivity studies demonstrated that twig oil had excellent antimicrobial and anti-wood-decay fungal activities, superior to those of the leaf oil. For the antimicrobial and anti-wood-decay fungal activities of the twig oil, the active compounds were determined to be tau-cadinol and alpha-cadinol.

摘要

对台湾锐叶木姜子叶和嫩枝中分离得到的挥发油的化学成分、抗菌及抗木材腐朽真菌活性进行了研究。采用克莱文杰型装置通过水蒸馏法从新鲜叶和嫩枝中分离挥发油,并通过气相色谱 - 氢火焰离子化检测器(GC - FID)和气相色谱 - 质谱联用仪(GC - MS)进行表征。叶油和枝油中分别鉴定出95种和52种化合物。叶油的主要成分是γ-广藿香烯(11.0%)、δ-杜松烯(6.3%)、反式-穆罗勒-3,5-二烯(5.9%)和β-芹子烯(5.3%),而枝油的主要成分是τ-杜松醇(13.1%)、β-芹子烯(9.6%)、反式-β-罗勒烯(6.2%)和α-杜松醇(7.7%)。生物活性研究表明,枝油具有优异的抗菌及抗木材腐朽真菌活性,优于叶油。对于枝油的抗菌及抗木材腐朽真菌活性,确定活性化合物为τ-杜松醇和α-杜松醇。

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