一名63岁女性，淋巴瘤缓解后出现进行性呼吸困难。

A 63-Year-Old Woman With Progressive Dyspnea After Remission of Lymphoma.

作者信息

Nishihara Tomoe, Nakano Hiroshi, Nogami Hiroko, Katahira Katsuyuki, Ishimatsu Akiko, Hashimoto Naozumi, Yokoi Toyoharu, Iwanaga Tomoaki

机构信息

Department of Psychosomatic Medicine, National Hospital Organization, Fukuoka National Hospital, Fukuoka, Japan; Department of Psychosomatic Medicine, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.

Department of Respiratory Medicine, National Hospital Organization, Fukuoka National Hospital, Fukuoka, Japan.

出版信息

Chest. 2017 Mar;151(3):e57-e62. doi: 10.1016/j.chest.2017.01.023.

DOI:10.1016/j.chest.2017.01.023

PMID:28279286

Abstract

A 63-year-old woman visited our hospital for a further evaluation of progressive dyspnea. She had developed a progressive airflow obstruction after 3 years' remission of non-Hodgkin's lymphoma (follicular mixed cell type), which had been treated with chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone). The patient's primary care physician had diagnosed her as having COPD and bronchial asthma and had treated her with medications including inhaled corticosteroids, tiotropium, and oral erythromycin. Her dyspnea had gradually worsened, however, and she had a score of 4 on the modified Medical Research Council dyspnea scale at the time of admission to our hospital.

摘要

一名63岁女性因进行性呼吸困难前来我院做进一步评估。她在非霍奇金淋巴瘤（滤泡混合细胞型）化疗（利妥昔单抗、环磷酰胺、阿霉素、长春新碱和泼尼松）缓解3年后出现了进行性气流阻塞。患者的初级保健医生诊断她患有慢性阻塞性肺疾病（COPD）和支气管哮喘，并用包括吸入性皮质类固醇、噻托溴铵和口服红霉素在内的药物对她进行了治疗。然而，她的呼吸困难逐渐加重，入院时改良医学研究委员会呼吸困难量表评分为4分。