Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.
Department of Microbiology, Infectious Diseases, and Immunology, Laval University, Quebec City, QC G1V 0A6, Canada.
Cell Host Microbe. 2017 Mar 8;21(3):294-296. doi: 10.1016/j.chom.2017.02.006.
It is only in the last decade that sub-cellular resolution of red cell invasion by the malaria parasite Plasmodium falciparum has been possible. Here we look back on the development of methodologies that led to this possibility and the subsequent advancements made in understanding this key event in malaria disease.
直到最近十年,才有可能从亚细胞水平解析疟原虫恶性疟原虫对红细胞的入侵。在这里,我们回顾了实现这一可能性的方法学的发展,以及随后在理解疟疾发病过程中的这一关键事件方面取得的进展。