Zeini Jahromi Nasim, Ghapanchi Janan, Pourshahidi Sara, Zahed Maryam, Ebrahimi Hooman
Dept. of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Dept. of Oral and Maxillofacial Medicine, Tehran University of Medical Sciences, Tehran, Iran.
J Dent (Shiraz). 2017 Mar;18(1):17-23.
Recurrent aphthous stomatitis (RAS) is one of the most common lesions in the oral cavity. Due to its multifactorial nature, there is no definitive treatment for RAS. Laser therapy is one of the suggested treatments to reduce patient's discomfort.
The purpose of the present clinical trial is to assess the effect of low and high level laser therapy on pain control and wound healing of RAS.
Thirty six patients with minor RAS were divided into three groups. Group 1 (n=14) received CO2 laser, group 2 (n=12) were treated with InGaAlP Diode laser and group 3 (n=10) received sham laser as placebo. All patients were evaluated daily up to 15 days after receiving one session of laser therapy. Pain severity before and after treatment, wound healing, patient's satisfaction, and functional disturbance before and after treatment were recorded for each patient.
According to statistical analysis, pain reduction after treatment in group 1 was 7.00±2.41, in group 2 was 2.08±2.31, and in group 3 was 1.40±1.77. In addition, a significant difference was observed in the reduction of functional complications in CO laser treated patients compared to the other two groups.
High-level laser treatment showed analgesic effects on RAS, but no healing was observed. Low-level laser therapy demonstrated no positive effect on recurrent aphthous ulcers.
复发性阿弗他口炎(RAS)是口腔中最常见的病变之一。由于其多因素性质,目前尚无针对RAS的明确治疗方法。激光治疗是减轻患者不适的建议治疗方法之一。
本临床试验的目的是评估低水平和高水平激光治疗对RAS疼痛控制和伤口愈合的效果。
36例轻度RAS患者分为三组。第1组(n = 14)接受二氧化碳激光治疗,第2组(n = 12)接受铟镓铝磷二极管激光治疗,第3组(n = 10)接受假激光作为安慰剂。所有患者在接受一次激光治疗后直至15天每天进行评估。记录每位患者治疗前后的疼痛严重程度、伤口愈合情况、患者满意度以及治疗前后的功能障碍。
根据统计分析,第1组治疗后疼痛减轻程度为7.00±2.41,第2组为2.08±2.31,第3组为1.40±1.77。此外,与其他两组相比,接受二氧化碳激光治疗的患者在功能并发症减少方面存在显著差异。
高水平激光治疗对RAS显示出镇痛作用,但未观察到愈合效果。低水平激光治疗对复发性阿弗他溃疡未显示出积极作用。