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低强度激光治疗复发性阿弗他口炎的临床评估

Clinical evaluation of low-level laser treatment for recurring aphthous stomatitis.

作者信息

De Souza Thaís Oricchio Fedri, Martins Marco Antonio Trevizani, Bussadori Sandra Kalil, Fernandes Kristianne Porta Santos, Tanji Edgar Yuji, Mesquita-Ferrari Raquel Agnelli, Martins Manoela Domingues

机构信息

Rehabilitation Sciences Department, Nove de Julho University, São Paulo, SP, Brazil.

出版信息

Photomed Laser Surg. 2010 Oct;28 Suppl 2:S85-8. doi: 10.1089/pho.2009.2661.

Abstract

OBJECTIVE

The aim of the present study was to assess the effect of low-level laser on the control of pain and the repair of recurring aphthous stomatitis (RAS).

BACKGROUND

One of the most frequent pathologic conditions in the oral cavity is RAS. This multifactor immunologic inflammatory lesion causes patient discomfort, and treatment is controversial because of its unknown etiology. A number of treatment modalities have been proposed, but none is definitive. Low-level laser treatment (LLLT) has been used for lesions of an inflammatory nature, not as an inhibitor of the process, but for its modulating action and reparative effect on tissues.

MATERIALS AND METHODS

Twenty patients with RAS were divided into one group treated with a topical corticoid agent (n = 5) and another group treated with laser (n = 15). Group I received conventional treatment with triamcinolone acetonide 4 times per day. The patients in Group II received laser treatment with an InGaA1P diode laser with wavelength of 670 nm, 50 mW, 3 J/cm(2) per point in daily sessions (once per day) on consecutive days. Both treatments were applied until the disappearance of the lesions. All patients were evaluated on a daily basis, and the following clinical parameters were determined during each session: pain intensity before and after treatment and clinical measurement of lesion size.

RESULTS

The results revealed that 75% of the patients reported a reduction in pain in the same session after laser treatment, and total regression of the lesion occurred after 4 days. Total regression in the corticoid group was from 5 to 7 days.

CONCLUSION

The use of LLLT under the conditions administered in the present study demonstrated analgesic and healing effects with regard to RAS.

摘要

目的

本研究旨在评估低强度激光对复发性阿弗他口炎(RAS)疼痛控制及修复的效果。

背景

口腔中最常见的病理状况之一是RAS。这种多因素免疫炎性病变会给患者带来不适,因其病因不明,治疗存在争议。已提出多种治疗方式,但均无定论。低强度激光治疗(LLLT)已用于炎性病变,并非作为该过程的抑制剂,而是因其对组织的调节作用和修复效果。

材料与方法

20例RAS患者分为两组,一组接受局部皮质类固醇药物治疗(n = 5),另一组接受激光治疗(n = 15)。第一组每天接受4次曲安奈德常规治疗。第二组患者接受波长为670 nm、功率50 mW、每点3 J/cm²的InGaAlP二极管激光治疗,每天一次,连续治疗。两种治疗均持续至病变消失。所有患者每天进行评估,每次治疗期间测定以下临床参数:治疗前后的疼痛强度以及病变大小的临床测量值。

结果

结果显示,75%的患者在激光治疗后的同一疗程中报告疼痛减轻,病变在4天后完全消退。皮质类固醇组的完全消退时间为5至7天。

结论

在本研究所用条件下使用LLLT对RAS具有镇痛和愈合作用。

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