Dua Monica M, Visser Brendan C
Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Dig Dis Sci. 2017 Jul;62(7):1738-1744. doi: 10.1007/s10620-017-4526-x. Epub 2017 Mar 9.
There are a number of surgical strategies for the treatment of chronic pancreatitis. The optimal intervention should provide effective pain relief, improve/maintain quality of life, preserve exocrine and endocrine function, and manage local complications. Pancreaticoduodenectomy was once the standard operation for patients with chronic pancreatitis; however, other procedures such as the duodenum-preserving pancreatic head resections and its variants have been introduced with good long-term results. Pancreatic duct drainage via a lateral pancreaticojejunostomy continues to be effective in ameliorating symptoms and expediting return to normal lifestyle in many patients. This review summarizes operative indications and gives an overview of the different surgical strategies in treating chronic pancreatitis.
治疗慢性胰腺炎有多种手术策略。最佳干预措施应能有效缓解疼痛、改善/维持生活质量、保留外分泌和内分泌功能并处理局部并发症。胰十二指肠切除术曾是慢性胰腺炎患者的标准手术;然而,其他手术,如保留十二指肠的胰头切除术及其变体已被采用,且长期效果良好。通过侧侧胰空肠吻合术进行胰管引流在许多患者中仍能有效缓解症状并加快恢复正常生活。本综述总结了手术适应证,并概述了治疗慢性胰腺炎的不同手术策略。